Koppen S, de Groot R, Neijens HJ, et al. Vaccine. 2004;22:3375–3385
Purpose of the Study.
Because the prevalence of allergic disease has increased in the last decades and one theory for the increase is immune dysregulation associated with hygiene and reduced infection, the study sought to determine if healthy children vaccinated at an early age have an increased risk for the development of allergic disease.
Epidemiologic studies with original data on the correlation between …