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To the Editor.—
The article by Hoorn et al1 surveys the frequency of hyponatremia in children seen in the emergency department of a large children's hospital. The survey included children who were hyponatremic on presentation (6% of 1586) and those who became hyponatremic when given intravenous (IV) fluid therapy (9% of 432). Both groups had nonosmotic (mostly hypovolemic) stimulated antidiuretic hormone (ADH) release and received electrolyte free water in excess of a renal excretory capacity, limited by …
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