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American Academy of Pediatrics
Commentary

Cerebral White Matter Injury of the Premature Infant—More Common Than You Think

Joseph J. Volpe
Pediatrics July 2003, 112 (1) 176-180; DOI: https://doi.org/10.1542/peds.112.1.176
Joseph J. Volpe
Children’s Hospital Harvard Medical School Boston, MA 02115
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Pediatrics
Vol. 112, Issue 1
1 Jul 2003
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Cerebral White Matter Injury of the Premature Infant—More Common Than You Think
Joseph J. Volpe
Pediatrics Jul 2003, 112 (1) 176-180; DOI: 10.1542/peds.112.1.176

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Cerebral White Matter Injury of the Premature Infant—More Common Than You Think
Joseph J. Volpe
Pediatrics Jul 2003, 112 (1) 176-180; DOI: 10.1542/peds.112.1.176
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  • Table of Contents

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  • Article
    • IMPORTANCE OF CEREBRAL WHITE MATTER INJURY
    • PREDOMINANCE OF NONCYSTIC CEREBRAL WHITE INJURY
    • NEW INSIGHTS FROM MRI/DIFFUSION-WEIGHTED MRI (DWI)
    • KEY QUESTIONS RAISED BY MRI/DWI
    • NEW NEUROPATHOLOGICAL INSIGHTS
    • IMPLICATIONS FOR PATHOGENESIS
    • POTENTIAL DELETERIOUS INTERACTION OF ISCHEMIA AND INFECTION
    • CONCLUSIONS
    • Footnotes
    • REFERENCES
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Subjects

  • Fetus/Newborn Infant
    • Fetus/Newborn Infant

Keywords

  • PVL, periventricular leukomalacia
  • MRI, magnetic resonance imaging
  • DEHSI, diffuse excessive high signal intensity
  • DWI, diffusion-weighted magnetic resonance imaging
  • ADC, apparent diffusion coefficient
  • ROS, reactive oxygen species
  • RNS, reactive nitrogen species
  • TLR, Toll-like receptor
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