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To the Editor.—
In a recent article by Chang,1 hospitalization records extracted from the Nationwide Inpatient Sample (NIS) were used to describe the epidemiology of Kawasaki syndrome (KS) during 1988–1997 in the United States. Chang reported that the incidence of KS increased over the 10-year study period. We question the accuracy of these findings, because the methods used for analyzing the NIS data were inappropriate.
The NIS is an annual stratified probability sample of hospitals from participating statewide data organizations designed to approximate a 20% sample of US community hospitals. It is produced as part of the Healthcare Cost and Utilization Project (HCUP), sponsored by the Agency for Healthcare Research and Quality in partnership with the states.2 Because the NIS is a complex stratified sample of hospitals, appropriately scaled discharge weights are provided with the …
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