Article Figures & Data
Figures
- Fig 1.
Study sample.
- Fig 2.
Model of the association between age of first sexual intercourse and HPV infection, as mediated by sexual and other risk behaviors and partner characteristics.
Tables
- TABLE 1.
Associations Between Age of First Sexual Intercourse and Sexual Behaviors, Other Risk Behaviors, and Partner Characteristics
Age of First Sexual Intercourse (Mean [SD]) Pearson Correlation Coefficient P Value* Sexual risk behaviors Sexual partners† 1 17.00 (1.7) <.0001 >1 16.02 (1.9) Frequency of vaginal intercourse† −0.08 .061 Condom use† Never/rarely 16.66 (1.6) .014 Sometimes 16.24 (2.1) Most/all of the time 16.90 (1.8) Oral contraceptive use† Yes 16.86 (1.8) .73 No 16.78 (1.6) History of STI Yes 16.26 (1.7) .059 No 16.77 (1.8) History of pregnancy Yes 16.11 (2.2) .009 No 16.79 (1.7) Other risk behaviors Current cigarette smoking Yes 16.26 (1.7) .002 No 16.86 (1.8) Drinking/drug use related to sexual behavior‡ Scale score 0 16.91 (1.8) .002 Scale score ≥1 16.40 (1.7) Partner characteristics Partner’s age§ 0.09 .079 Partner’s race§ White 16.70 (1.7) .24 Black 16.40 (2.2) Hispanic 16.91 (1.5) Asian 17.08 (1.9) Partner’s number of sexual partners§ −.092 .038 SD indicates standard deviation.
↵* The P value is derived from a Pearson correlation coefficient if the behavioral/partner characteristic variable is continuous and from a t test or analysis of variance procedure if the behavioral/partner characteristic variable is categorical.
↵† These variables were assessed during the 6 months before testing positive for HPV.
↵‡ Self-report of risky sexual behaviors while using alcohol or illicit drugs, measured using a 9-point scale.
↵§ Assessed for main sexual partner.
- TABLE 2.
Associations Between HPV Infection and Sexual Behaviors, Other Risk Behaviors, and Partner Characteristics*
HPV-Positive (N [%]) Mean (SD), HPV-Positive Mean (SD), HPV-Negative P Value† Sexual risk behaviors Number of sexual partners‡ 1 152 (42.2) .001 >1 100 (69.4) Frequency of vaginal intercourse‡ 38.5 (47.5) 27.3 (38.6) .004 Condom use‡ Never/rarely 67 (46.5) .07 Sometimes 49 (61.3) Most/all of the time 132 (47.8) Oral contraceptive use‡ Yes 64 (49.6) .85 No 59 (50.9) History of STI Yes 37 (74.0) .001 No 215 (47.5) History of pregnancy Yes 33 (61.1) .08 No 219 (48.7) Other risk behaviors Current cigarette smoking Yes 72 (61.5) .005 No 180 (46.6) Drinking/drug use related to sexual behavior§ Scale score 0 140 (44.3) .001 Scale score ≥1 112 (59.6) Partner characteristics Partner’s age‖ 21.9 (3.3) 20.7 (2.3) .0001 Partner’s race‖ White 126 (42.4) .001 Black 51 (87.9) Hispanic 39 (60.9) Asian 13 (28.3) Other 23 (59.0) Partner’s number of sexual partners‖ 7.8 (10.2) 3.3 (4.8) .0001 SD indicates standard deviation.
↵* Several of these associations have been reported previously, using different sample selection and methods of analysis, in Ho et al2 and Burk et al.18
↵† The P value is derived from a χ2 statistic if the behavioral/partner characteristic variable is categorical and from a t test or analysis of variance procedure if the behavioral/partner characteristic variable is continuous.
↵‡ These variables were assessed during the 6 months before testing positive for HPV.
↵§ Self-report of risky sexual behaviors while using alcohol or illicit drugs, measured using a 9-point scale.
↵‖ Assessed for main sexual partner.
- TABLE 3.
GEE Models Examining the Association Between Age of First Sexual Intercourse and HPV Infection
HPV infection regressed on age of first sexual intercourse Variable β Estimate Standard Error Odds Ratio 95% Confidence Interval P Value Age of first sexual intercourse* −0.20 0.05 0.82 0.74 0.90 .0001 HPV infection regressed on age of first sexual intercourse controlling for risk variables, partner characteristics, and participant race Variable β Estimate Standard Error Odds Ratio 95%Confidence Interval P Value Age of first sexual intercourse* −0.16 0.06 0.85 0.76 0.97 .013 Number of sexual partners† 0.50 0.14 1.65 1.26 2.16 .0003 History of STI 0.80 0.34 2.23 1.14 4.35 .019 Drinking/drug use related to sexual behavior‡ 2.95 0.80 19.1 4.01 91.8 .0002 Partner’s lifetime number of sexual partners§ 0.06 0.03 1.06 1.01 1.12 .014 Partner’s age§ 0.14 0.05 1.15 1.04 1.27 .006 Participant’s race‖ White −1.00 0.37 0.37 0.18 0.76 .007 Black 1.58 0.55 4.85 1.63 14.3 .004 Hispanic 0.0008 0.45 1.0 0.42 2.41 1.00 Asian −1.36 0.48 0.26 0.10 0.65 .004 ↵* Age assessed as a continuous variable; odds are per year of age.
↵† This variable was assessed during the 6 months before testing positive for HPV.
↵‡ Self-report of risky sexual behaviors while using alcohol or illicit drugs, measured using a 9-point scale: scale dichotomized into ever versus never practiced risky behaviors while using alcohol or illicit drugs.
↵§ Assessed for main sexual partner.
↵‖ “Other” race served as the reference group.
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