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American Academy of Pediatrics
Letter to the Editor

Amoxycillin-Clavulanic Acid–Related Tooth Discoloration in Children

M. Garcia-López, M. Martinez-Blanco, I. Martinez-Mir and V. Palop
Pediatrics September 2001, 108 (3) 819; DOI: https://doi.org/10.1542/peds.108.3.819-a
M. Garcia-López
1Primary Care Pediatric Clinic
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M. Martinez-Blanco
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I. Martinez-Mir
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V. Palop
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To the Editor.

The voluntary communication of isolated adverse drug reactions (ADRs) is the most effective means for the postmarketing identification of rare, serious adverse reactions. These communications can be made to Drug Surveillance Services or to medical and scientific journals. The publication of case reports is an important primary source of information on ADRs and contributes to the improvement of drug safety.1 We present 3 cases of dental discoloration in children related to the administration of amoxicillin-clavulanic acid. No similar cases have been published in either clinical trials or as isolated cases.

Case 1 was a 6-year-old girl with a history of allergic rhinitis and asthma subjected to chronic treatment with budesonide …

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Pediatrics
Vol. 108, Issue 3
1 Sep 2001
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Amoxycillin-Clavulanic Acid–Related Tooth Discoloration in Children
M. Garcia-López, M. Martinez-Blanco, I. Martinez-Mir, V. Palop
Pediatrics Sep 2001, 108 (3) 819; DOI: 10.1542/peds.108.3.819-a

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Amoxycillin-Clavulanic Acid–Related Tooth Discoloration in Children
M. Garcia-López, M. Martinez-Blanco, I. Martinez-Mir, V. Palop
Pediatrics Sep 2001, 108 (3) 819; DOI: 10.1542/peds.108.3.819-a
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