Skip to main content

Advertising Disclaimer »

Main menu

  • Journals
    • Pediatrics
    • Hospital Pediatrics
    • Pediatrics in Review
    • NeoReviews
    • AAP Grand Rounds
    • AAP News
  • Authors/Reviewers
    • Submit Manuscript
    • Author Guidelines
    • Reviewer Guidelines
    • Open Access
    • Editorial Policies
  • Content
    • Current Issue
    • Online First
    • Archive
    • Blogs
    • Topic/Program Collections
    • AAP Meeting Abstracts
  • Pediatric Collections
    • COVID-19
    • Racism and Its Effects on Pediatric Health
    • More Collections...
  • AAP Policy
  • Supplements
    • Supplements
    • Publish Supplement
  • Multimedia
    • Video Abstracts
    • Pediatrics On Call Podcast
  • Subscribe
  • Alerts
  • Careers
  • Other Publications
    • American Academy of Pediatrics

User menu

  • Log in
  • My Cart

Search

  • Advanced search
American Academy of Pediatrics

AAP Gateway

Advanced Search

AAP Logo

  • Log in
  • My Cart
  • Journals
    • Pediatrics
    • Hospital Pediatrics
    • Pediatrics in Review
    • NeoReviews
    • AAP Grand Rounds
    • AAP News
  • Authors/Reviewers
    • Submit Manuscript
    • Author Guidelines
    • Reviewer Guidelines
    • Open Access
    • Editorial Policies
  • Content
    • Current Issue
    • Online First
    • Archive
    • Blogs
    • Topic/Program Collections
    • AAP Meeting Abstracts
  • Pediatric Collections
    • COVID-19
    • Racism and Its Effects on Pediatric Health
    • More Collections...
  • AAP Policy
  • Supplements
    • Supplements
    • Publish Supplement
  • Multimedia
    • Video Abstracts
    • Pediatrics On Call Podcast
  • Subscribe
  • Alerts
  • Careers

Discover Pediatric Collections on COVID-19 and Racism and Its Effects on Pediatric Health

American Academy of Pediatrics

A statement of reaffirmation for this policy was published at

  • 120(3):683

revised

  • 128(2):393
AMERICAN ACADEMY OF PEDIATRICS

Health Supervision for Children With Down Syndrome

Committee on Genetics
Pediatrics February 2001, 107 (2) 442-449; DOI: https://doi.org/10.1542/peds.107.2.442
  • Article
  • Figures & Data
  • Info & Metrics
  • Comments
Loading
Download PDF

Abstract

These guidelines are designed to assist the pediatrician in caring for the child in whom the diagnosis of Down syndrome has been confirmed by karyotype. Although the pediatrician's initial contact with the child is usually during infancy, occasionally the pregnant woman who has been given the prenatal diagnosis of Down syndrome will be referred for counseling. Therefore, these guidelines offer advice for this situation as well.

Children with Down syndrome have multiple malformations and mental impairment because of the presence of extra genetic material from chromosome 21. Although the phenotype is variable, usually there is enough consistency to enable the experienced clinician to suspect the diagnosis. Among the more common physical features are hypotonia, small brachycephalic head, epicanthic folds, flat nasal bridge, upward slanting palpebral fissures, Brushfield spots, small mouth, small ears, excessive skin at the nape of the neck, single transverse palmar crease, and short fifth finger with clinodactyly. A wide space, often with a deep fissure between the first and second toes, is also common. The degree of mental impairment is variable, ranging from mild (IQ: 50–70) to moderate (IQ: 35–50), and only occasionally to severe (IQ: 20–35). There is an increased risk of congenital heart defects (50%); leukemia (<1%); hearing loss (75%); otitis media (50%–70%); Hirschsprung disease (<1%); gastrointestinal atresias (12%); eye disease (60%), including cataracts (15%) and severe refractive errors (50%); acquired hip dislocation (6%); obstructive sleep apnea (50%–75%); and thyroid disease (15%). The social quotient may be improved with early intervention techniques, although the level of function is exceedingly variable. Children with Down syndrome often function better in social situations than might be expected from their IQ.

In approximately 95% of children with Down syndrome, the condition is because of nonfamilial trisomy 21. In approximately 3% to 4% of persons with the Down syndrome phenotype, the extra chromosomal material is the result of an unbalanced translocation between chromosome 21 and another acrocentric chromosome, usually chromosome 14. Approximately three fourths of these unbalanced translocations are de novo, and approximately one fourth are the result of familial translocations. If the child has a translocation, a balanced translocation must be excluded in the parents. If there is a translocation in either parent, additional familial studies and counseling should be instituted. In the remaining 1% to 2% of persons with the Down syndrome phenotype, 2 cell lines are present: 1 normal and 1 trisomy 21. This condition is called mosaicism. These persons, on average, may be phenotypically less severely affected than persons with trisomy 21 or translocated chromosome 21, but their conditions are generally indistinguishable in all other aspects.

Medical management, home environment, education, and vocational training can significantly affect the level of functioning of children and adolescents with Down syndrome and facilitate their transition to adulthood. The following outline is designed to help the pediatrician to care for children with Down syndrome and their families.1–4 It is organized by the issues that need to be addressed in the various age groups (see Table 1).

View this table:
  • View inline
  • View popup
Table 1.

Health Supervision for Children With Down Syndrome—Committee on Genetics*

Several areas require ongoing assessment throughout childhood and should be reviewed periodically at developmentally appropriate ages. These include the following:

  • Personal support available to family.

  • All other financial and medical support programs for which the child and family may be eligible.

  • Supplemental Security Income benefits.

  • Injury and abuse prevention with special consideration of developmental skills.

  • Diet and exercise to maintain appropriate weight.

THE PRENATAL VISIT

Pediatricians may be asked to counsel a family in which a fetus has a genetic disorder. In some settings, the pediatrician may be the primary resource for counseling. At other times, counseling may have been provided for the family by a clinical geneticist, obstetrician, or developmental pediatrician. In addition, parents may have received information from a Down syndrome program, a national Down syndrome organization, or an Internet site. Because of a previous relationship with the family, the pediatrician may be asked to review this information and assist in the decision-making process. As appropriate, the pediatrician should discuss the following topics with the family:

  1. The prenatal laboratory or fetal imaging studies leading to the diagnosis.

  2. The mechanism for occurrence of the disorder in the fetus and the potential recurrence rate for the family.

  3. The prognosis and manifestations, including the wide range of variability seen in infants and children with Down syndrome.

  4. When applicable, additional studies that may refine the estimation of the prognosis (eg, fetal echocardiogram, ultrasound examination for gastrointestinal malformations).

  5. Currently available treatments and interventions. This discussion needs to include the efficacy, potential complications and adverse effects, costs, and other burdens associated with these treatments. Discuss early intervention resources, parent support programs, and any plausible future treatments.

  6. The options available to the family for management and rearing of the child using a nondirective approach. In cases of early prenatal diagnosis, this may include discussion of pregnancy continuation or termination, rearing the child at home, foster care placement, and adoption.

If the pregnancy is continued, a plan for delivery and neonatal care must be developed with the obstetrician and the family. Offer parent-to-parent contact. As the pregnancy progresses, additional studies may be valuable for modifying this management plan (eg, detection of a complex heart defect by echocardiography). When appropriate, referral to a clinical geneticist should be considered for a more extended discussion of clinical outcomes and variability, recurrence rates, future reproductive options, and evaluation of the risks for other family members.

HEALTH SUPERVISION FROM BIRTH TO 1 MONTH: NEWBORNS

Examination

Confirm the diagnosis of Down syndrome and review the karyotype with the parents. Review the phenotype. Discuss the specific findings with both parents whenever possible, and talk about the following potential clinical manifestations associated with the syndrome. These may have to be reviewed again at a subsequent meeting.

Discuss and Review

  • Hypotonia

  • Facial appearance

Evaluate for

  • Feeding problems

  • Strabismus, cataracts, and nystagmus at birth or by 6 months

  • Congenital hearing loss with objective testing, such as brainstem auditory evoked response or otoacoustic emission at birth or by 3 months5

  • Heart defects (approximately 50% risk). Perform cardiac evaluation (consultation by a cardiologist with expertise and experience in pediatric patients and echocardiogram recommended).

  • Duodenal atresia

  • Constipation with increased risk of Hirschsprung disease

  • Leukemia—more common in children with Down syndrome than in the general population, but still rare (<1%); leukemoid reactions, on the other hand, are relatively common as is polycythemia (18%). Obtain complete blood count.

  • Congenital hypothyroidism (1% risk)

  • Respiratory tract infections

Anticipatory Guidance

  • Discuss increased susceptibility to respiratory tract infection

  • Discuss the availability and efficacy of early intervention.

  • Discuss the early intervention services in the community.

  • Inform the family of the availability of support and advice from the parents of other children with Down syndrome.

  • Supply names of Down syndrome support groups and current books and pamphlets (see “Bibliography and Resources for New Parents”).

  • Discuss the strengths of the child and positive family experiences.

  • Check on individual resources for support, such as family, clergy, and friends.

  • Talk about how and what to tell other family members and friends. Review methods of coping with long-term disabilities.

  • Review the recurrence risk in subsequent pregnancies and the availability of prenatal diagnosis.

  • Discuss unproven therapies.6–12

HEALTH SUPERVISION FROM 1 MONTH TO 1 YEAR: INFANCY

Examination

Physical Examination and Laboratory Studies

  • Review the risk of serous otitis media (50%–70%). If the tympanic membranes cannot be visualized, or if the parents express any concern about their child's hearing, refer the infant to an otolaryngologist. Review the prior hearing evaluation (brainstem auditory evoked response and otoacoustic emission and refer back to the otolaryngologist and audiologist if the initial evaluation was abnormal for follow up examination and testing. A behavioral audiogram should be obtained at 1 year in all children examined.

  • Check for strabismus, cataracts, and nystagmus by 6 months, if not done at birth. Check the infant's vision at each visit, using developmentally appropriate subjective and objective criteria. By 6 months, refer the infant to a pediatric ophthalmologist or an ophthalmologist with special expertise and experience with infants with disabilities.

  • Verify results of newborn thyroid function screen. Because of increased risk of acquired thyroid disease, repeat at 6 and 12 months and then annually.13,14

  • Administer pneumococcal vaccine, as well as other vaccines recommended for all children unless there are specific contraindications.

Anticipatory Guidance

  • Review the infant's growth and development relative to other children with Down syndrome (Figs 1–4).15

  • Review availability of Down syndrome support groups (see “Bibliography and Resources for New Parents”).

  • Assess the emotional status of parents and intrafamily relationships. Educate and support siblings and discuss sibling adjustments. At 6 to 12 months, review the psychological support and intrafamily relationships, including long-term planning, financial planning, and guardianship.

  • Review the early intervention services relative to the strengths and needs of the infant and family (see “Bibliography and Resources for New Parents”).

  • Review the family's understanding of the risk of recurrence of Down syndrome and the availability of prenatal diagnosis.

Fig. 1.
  • Download figure
  • Open in new tab
  • Download powerpoint
Fig. 1.

Percentiles for height and weight of females with Down syndrome, 1 to 36 months of age. From Cronk C, Crocker AC, Pueschel SM, et al. Growth charts for children with Down syndrome: 1 month to 18 years of age.Pediatrics. 1988;81:102–110.

Fig. 2.
  • Download figure
  • Open in new tab
  • Download powerpoint
Fig. 2.

Percentiles for height and weight of females with Down syndrome, 2 to 18 years of age. From Cronk C, Crocker AC, Pueschel SM, et al. Growth charts for children with Down syndrome: 1 month to 18 years of age.Pediatrics. 1988;81:102–110.

Fig. 3.
  • Download figure
  • Open in new tab
  • Download powerpoint
Fig. 3.

Percentiles for height and weight of males with Down syndrome, 1 to 36 months of age. From Cronk C, Crocker AC, Pueschel SM, et al. Growth charts for children with Down syndrome: 1 month to 18 years of age.Pediatrics. 1988;81:102–110.

Fig. 4.
  • Download figure
  • Open in new tab
  • Download powerpoint
Fig. 4.

Percentiles for height and weight of males with Down syndrome, 2 to 18 years of age. From Cronk C, Crocker AC, Pueschel SM, et al. Growth charts for children with Down syndrome: 1 month to 18 years of age.Pediatrics. 1988;81:102–110.

HEALTH SUPERVISION FROM 1 TO 5 YEARS: EARLY CHILDHOOD

  • Obtain a history and perform a physical examination with attention to growth and developmental status.

  • Review the risk of serous otitis media with hearing loss. If the tympanic membranes cannot be completely visualized (because of the frequent problem of stenotic ear canals), check the child's audiogram every 6 months up to 3 years or up to when a pure tone audiogram is obtained. Refer the child to an otolaryngologist or audiologist if necessary (approximately 50%–70% risk of serous otitis media between 3 and 5 years).

  • Check the child's vision annually, using developmentally appropriate subjective and objective criteria. Refer the child to a pediatric ophthalmologist or ophthalmologist with special expertise and experience with children with disabilities every 2 years (approximately 50% risk of refractive errors between 3 and 5 years).

  • At 3 to 5 years, obtain radiographs for evidence of atlantoaxial instability or subluxation. These may be obtained once during the preschool years. The need for these studies has been questioned, but they may be required for participation in the Special Olympics. These studies are more important for children who may participate in contact sports and are indicated in those who are symptomatic.16–19

  • Perform thyroid screening tests annually.

  • Discuss symptoms related to obstructive sleep apnea, including snoring, restless sleep, and sleep position. Refer to a specialist as indicated.20

Anticipatory Guidance

  • Review early intervention, including physical therapy, occupational therapy, and speech, in the preschool program and discuss future school placement and performance.

  • Discuss future pregnancy planning, risk of recurrence of Down syndrome, and prenatal diagnosis.

  • Assess the child's behavior, and talk about behavioral management, sibling adjustments, socialization, and recreational skills.

  • Encourage families to establish optimal dietary and physical exercise patterns that will prevent obesity.

HEALTH SUPERVISION FROM 5 TO 13 YEARS: LATE CHILDHOOD

  • Obtain a history and perform a physical examination with attention to growth and developmental status.

  • Obtain audiologic evaluation annually.

  • Obtain ophthalmologic evaluation annually.

  • Perform thyroid screening tests annually (3%–5% risk of hypothyroidism).

  • If appropriate, discuss skin problems: very dry skin and other skin problems are particularly common in patients with Down syndrome.

  • Discuss symptoms related to obstructive sleep apnea, including snoring, restless sleep, and sleep position. Refer to a specialist as indicated.20

Anticipatory Guidance

  • Review the child's development and appropriateness of school placement and developmental intervention.

  • Discuss socialization, family status, and relationships, including financial arrangements and guardianship.

  • Discuss the development of age-appropriate social skills, self-help skills, and the development of a sense of responsibility.

  • Discuss psychosexual development, physical and sexual development, menstrual hygiene and management, fertility, and contraception.21

  • Discuss the need for gynecologic care in the pubescent female. Talk about the recurrence risk of Down syndrome with the patient and her family if she were to become pregnant.22 Review the fact that although there have been 2 case reports in which a male has reproduced, males with Down syndrome are usually infertile.22

HEALTH SUPERVISION FROM 13 TO 21 YEARS OR OLDER: ADOLESCENCE TO EARLY ADULTHOOD

Examination

  • Perform physical examination including CBC and thyroid function tests.

  • Obtain annual audiologic evaluation.

  • Obtain annual ophthalmologic evaluation.

  • Discuss skin care.

Anticipatory Guidance

  • Discuss issues related to transition into adulthood.

  • Discuss appropriateness of school placement with emphasis on adequate vocational training within the school curriculum.20,23

  • Talk about the recurrence risk of Down syndrome with the patient and her family if she were to become pregnant.22

  • Discuss sexuality and socialization. Discuss the need for and degree of supervision and/or the need for contraception. Make recommendations for routine gynecologic care.

  • Discuss group homes and independent living opportunities, workshop settings, and other community-supported employment.

  • Discuss intrafamily relationships, financial planning, and guardianship.

  • Facilitate transfer to adult medical care.

Committee on Genetics, 2000–2001

Jaime L. Frias, MD

Celia Kaye, MD, PhD

John B. Moeschler, MD

Susan R. Panny, MD

Tracy L. Trotter, MD

Liaisons

Felix de la Cruz, MD, MPH

National Institutes of Health

James W. Hanson, MD

American College of Medical Genetics

Michele Lloyd-Puryear, MD, PhD

Health Resources and Services Administration

Cynthia A. Moore, MD, PhD

Centers for Disease Control and Prevention

John Williams III, MD

American College of Obstetricians and Gynecologists

Section Liaison

H. Eugene Hoyme, MD

Section on Genetics

Consultants

Marilyn J. Bull, MD

William I. Cohen, MD

Franklin Desposito, MD

Beth A. Pletcher, MD

Nancy Roizen, MD

Rebecca Wappner, MD

Staff

Lauri A. Hall

BIBLIOGRAPHY AND RESOURCES FOR NEW PARENTS

Footnotes

  • The recommendations in this policy statement do not indicate an exclusive course of treatment for children with genetic disorders, but are meant to supplement anticipatory guidelines available for treating the healthy child provided in the AAP publication, “Guidelines for Health Supervision.” They are intended to assist the pediatrician in helping children with genetic conditions to participate fully in life. Diagnosis and treatment of genetic disorders are changing rapidly. Therefore, pediatricians are encouraged to view these guidelines in the light of evolving scientific information. Clinical geneticists may be a valuable resource for the pediatrician seeking additional information or consultation.

REFERENCES

    1. American Academy of Pediatrics Committee on Genetics
    (1994) Health supervision for children with Down syndrome. Pediatrics 93:855–859.
    OpenUrlAbstract/FREE Full Text
    1. Cohen WI
    (1996) Health care guidelines for individuals with Down syndrome (Down syndrome preventive medical checklist). Down Syndrome Q 1:1–10.
    OpenUrl
    1. Cooley WC,
    2. Graham JM Jr.
    (1991) Down syndrome: an update and review for the primary pediatrician. Clin Pediatr (Phila) 30:233–253.
    OpenUrlFREE Full Text
  1. de la Cruz F. Medical management of mongolism or Down syndrome. In: Mittler P, de Jong JM, eds. Biomedical Aspects. Research to Practice in Mental Retardation: Fourth Congress of the International Association for the Scientific Study of Mental Deficiency. Vol 3. Baltimore, MD: University Park Press; 1977;221–228
    1. Dahle AJ,
    2. McCollister FP
    (1986) Hearing and otologic disorders in children with Down syndrome. Am J Ment Defic 90:636–642.
    OpenUrlPubMed
  2. National Down Syndrome Congress. Position Statement on Sicca Cell Therapy. Atlanta, GA: National Down Syndrome Congress; 1989
    1. Nickel RE
    (1996) Controversial therapies for young children with developmental disabilities. Infants Young Child 8:29–40.
    OpenUrlCrossRef
  3. National Down Syndrome Society. Position Statement on Vitamin Related Therapies. New York, NY: National Down Syndrome Society; 1997. Available at: http://www.ndss.org Accessed June 1998
  4. National Down Syndrome Society. Position Statement on Use of Piracetam. New York, NY: National Down Syndrome Society; 1996. Available at: http://www.ndss.org Accessed June 1998
  5. National Down Syndrome Congress. National intervention in children with Down syndrome. Atlanta, GA: National Down Syndrome Congress; 1999. Available at: http://www.ndsccenter.org Accessed November 1999
  6. Spigelblatt L, Laine-Ammara G, Pless IB, Guyver A. The use of alternative medicine by children. Pediatrics. 1994;94(6 pt 1):811–814
  7. American College of Medical Genetics. Statement on Nutritional Supplements and Piracetam for Children With Down Syndrome. Bethesda, MD: American College of Medical Genetics; 1996
    1. Cutler AT,
    2. Benezra-Obeiter R,
    3. Brink SJ
    (1986) Thyroid function in young children with Down syndrome. Am J Dis Child 140:479–483.
    OpenUrlCrossRefPubMed
    1. Karlsson G,
    2. Gustafsson J,
    3. Hedov G,
    4. Ivarsson SA,
    5. Anneren G
    (1998) Thyroid dysfunction in Down's syndrome: relation to age and thyroid autoimmunity. Arch Dis Child 79:242–245.
    OpenUrlAbstract/FREE Full Text
    1. Cronk C,
    2. Crocker AC,
    3. Pueschel SM,
    4. et al.
    (1988) Growth charts for children with Down syndrome: 1 month to 18 years of age. Pediatrics 81:102–110.
    OpenUrlAbstract/FREE Full Text
    1. Davidson RG
    (1988) Atlantoaxial instability in individuals with Down syndrome: a fresh look at the evidence. Pediatrics 81:857–865.
    OpenUrlAbstract/FREE Full Text
  8. Msall ME, Reese ME, DiGaudio K, Griswold K, Granger CV, Cooke RE. Symptomatic atlantoaxial instability associated with medical and rehabilitative procedures in children with Down syndrome.Pediatrics. 1990;85(3 pt 2):447–449
    1. Pueschel SM,
    2. Findley TW,
    3. Furia J,
    4. Gallagher PL,
    5. Scola FH,
    6. Pezzullo JC
    (1987) Atlantoaxial instability in Down syndrome: roentgenographic, neurologic, and somatosensory evoked potential studies. J Pediatr 110:515–521.
    OpenUrlCrossRefPubMed
    1. Pueschel SM,
    2. Scola FH
    (1987) Atlantoaxial instability in individuals with Down syndrome: epidemiologic, radiographic, and clinical studies. Pediatrics 80:555–560.
    OpenUrlAbstract/FREE Full Text
  9. Pueschel SM, Pueschel JK, eds. Biomedical Concerns in Persons With Down Syndrome. Baltimore, MD: Brookes Publishing; 1992
  10. de la Cruz FF, LaVeck GD, eds. Human Sexuality and the Mentally Retarded. New York, NY: Brunner/Mazel; 1973
  11. Jagiello G. Reproduction in Down syndrome. In: de la Cruz FF, Gerald PS, eds. Trisomy 21 (Down Syndrome): Research Perspectives. Baltimore, MD: University Park Press; 1981;151–162
  12. Fenner ME, Hewitt KE, Torpy DM. Down's syndrome: intellectual behavioural functioning during adulthood. J Ment Defic Res. 1987;31(pt 3):241–249

Bibliography

  1. BU1.
    Cairo S, Cairo J, Cairo T. Our Brother Has Down's Syndrome: An Introduction for Children. Toronto, Ontario: Annick Press Ltd; 1985
  2. BU2.
    Hanson MJ. Teaching the Infant With Down Syndrome: A Guide for Parents and Professionals. 2nd ed. Austin, TX: Pro-Ed; 1987
  3. BU3.
    Pueschel SM. A parent's guide to Down syndrome. Baltimore, MD: Brookes Publishing; 1990
  4. BU4.
    Stray-Gunderson K. Babies With Down Syndrome: A New Parents Guide. Kensington, MD: Woodbine House; 1986 (English and Spanish editions)

Resources

  1. BU1.
    March of Dimes, Birth Defects Foundation, 1275 Mamaroneck Ave, White Plains, NY 10605; Telephone: 914/428–7100
  2. BU2.
    National Down Syndrome Congress, 1605 Chantilly Dr, Suite 250, Atlanta, GA 30324; Telephone: 404/633–1555 or 800/232–6372
  3. BU3.
    National Down Syndrome Society, 666 Broadway, New York, NY 10012; Telephone: 212/460–9330 or 800/221–4602
  • Copyright © 2001 American Academy of Pediatrics
PreviousNext
Back to top

Advertising Disclaimer »

In this issue

Pediatrics
Vol. 107, Issue 2
1 Feb 2001
  • Table of Contents
  • Index by author
View this article with LENS
PreviousNext
Email Article

Thank you for your interest in spreading the word on American Academy of Pediatrics.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Health Supervision for Children With Down Syndrome
(Your Name) has sent you a message from American Academy of Pediatrics
(Your Name) thought you would like to see the American Academy of Pediatrics web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Request Permissions
Article Alerts
Log in
You will be redirected to aap.org to login or to create your account.
Or Sign In to Email Alerts with your Email Address
Citation Tools
Health Supervision for Children With Down Syndrome
Committee on Genetics
Pediatrics Feb 2001, 107 (2) 442-449; DOI: 10.1542/peds.107.2.442

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Health Supervision for Children With Down Syndrome
Committee on Genetics
Pediatrics Feb 2001, 107 (2) 442-449; DOI: 10.1542/peds.107.2.442
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Print
Download PDF
Insight Alerts
  • Table of Contents

Jump to section

  • Article
    • Abstract
    • THE PRENATAL VISIT
    • HEALTH SUPERVISION FROM BIRTH TO 1 MONTH: NEWBORNS
    • HEALTH SUPERVISION FROM 1 MONTH TO 1 YEAR: INFANCY
    • HEALTH SUPERVISION FROM 1 TO 5 YEARS: EARLY CHILDHOOD
    • HEALTH SUPERVISION FROM 5 TO 13 YEARS: LATE CHILDHOOD
    • HEALTH SUPERVISION FROM 13 TO 21 YEARS OR OLDER: ADOLESCENCE TO EARLY ADULTHOOD
    • BIBLIOGRAPHY AND RESOURCES FOR NEW PARENTS
    • Footnotes
    • REFERENCES
    • Bibliography
    • Resources
  • Figures & Data
  • Info & Metrics
  • Comments

Related Articles

  • AAP Publications Reaffirmed and Retired
  • Health Supervision for Children With Down Syndrome
  • PubMed
  • Google Scholar

Cited By...

  • Fifteen-minute consultation: The review of a child with trisomy 21 (Downs syndrome)
  • What people with Down Syndrome can teach us about cardiopulmonary disease
  • Cardiac Screening in Infants With Down Syndrome
  • Down syndrome, insulin-dependent diabetes mellitus and hyperthyroidism: a rare association
  • Managing the care of adults with Down's syndrome
  • Core Concepts: Chromosome Aneuploidies
  • Best Practices in Managing Transition to Adulthood for Adolescents With Congenital Heart Disease: The Transition Process and Medical and Psychosocial Issues: A Scientific Statement From the American Heart Association
  • Medically Underserved Girls Receive Less Evaluation for Short Stature
  • Congenital heart defects are under-recognised in adult patients with Down's syndrome
  • Access to Genetic Counseling for Children With Autism, Down Syndrome, and Intellectual Disabilities
  • Increased Prevalence of Renal and Urinary Tract Anomalies in Children With Down Syndrome
  • Postnatal Diagnosis of Down Syndrome: Synthesis of the Evidence on How Best to Deliver the News
  • Health of Children 3 to 17 Years of Age With Down Syndrome in the 1997-2005 National Health Interview Survey
  • Increase in Incidence of Medically Treated Thyroid Disease in Children With Down Syndrome After Rerelease of American Academy of Pediatrics Health Supervision Guidelines
  • Promoting the Participation of Children With Disabilities in Sports, Recreation, and Physical Activities
  • Index of Suspicion
  • Adults with Down's syndrome: the prevalence of complications and health care in the community
  • Down's syndrome and early cataract
  • Neurodevelopmental Implications of Congenital Heart Disease
  • Longitudinal study of thyroid function in Down's syndrome in the first two decades
  • How often should we screen children with Down's syndrome for hypothyroidism?
  • Subclinical hypothyroidism and Down's syndrome; studies on myocardial structure and function
  • Caring for children with Down syndrome: Pediatricians should strive for early diagnosis; monitor for medical, developmental conditions
  • Health Supervision for Children With Down Syndrome
  • Google Scholar

More in this TOC Section

  • Disaster Planning for Schools
  • Exposure to Nontraditional Pets at Home and to Animals in Public Settings: Risks to Children
  • Medical Emergencies Occurring at School
Show more AMERICAN ACADEMY OF PEDIATRICS

Similar Articles

Subjects

  • Genetics
    • Genetics
  • Journal Info
  • Editorial Board
  • Editorial Policies
  • Overview
  • Licensing Information
  • Authors/Reviewers
  • Author Guidelines
  • Submit My Manuscript
  • Open Access
  • Reviewer Guidelines
  • Librarians
  • Institutional Subscriptions
  • Usage Stats
  • Support
  • Contact Us
  • Subscribe
  • Resources
  • Media Kit
  • About
  • International Access
  • Terms of Use
  • Privacy Statement
  • FAQ
  • AAP.org
  • shopAAP
  • Follow American Academy of Pediatrics on Instagram
  • Visit American Academy of Pediatrics on Facebook
  • Follow American Academy of Pediatrics on Twitter
  • Follow American Academy of Pediatrics on Youtube
  • RSS
American Academy of Pediatrics

© 2021 American Academy of Pediatrics