Effect of Cisapride on the QT Interval in Infants With Gastroesophageal Reflux

Vikram Khoshoo; Dean Edell; Robert Clarke

doi:10.1542/peds.105.2.e24

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ELECTRONIC ARTICLE

Effect of Cisapride on the QT Interval in Infants With Gastroesophageal Reflux

Vikram Khoshoo, Dean Edell and Robert Clarke

Pediatrics February 2000, 105 (2) e24; DOI: https://doi.org/10.1542/peds.105.2.e24

Vikram Khoshoo

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Dean Edell

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Robert Clarke

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Table 1.

QTc Before and After Cisapride Treatment

	Group A	Group B
Number of infants	60	40
Age in mo
Mean (SD)	4.8 (1.1)	5.8 (1.0)
Range	3–7	3.5–7
QTc interval in milliseconds
Before initiation of treatment
Mean (SD)	390 (18)
Number with QTc >440	0
After initiation of treatment
Mean (SD)	400 (20)	403 (27)
Number with QTc >440	1	1
Number with increase in QTc >10	30
Number with arrhythmia	0	0

SD indicates standard deviation; QTc, corrected QT interval.

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Pediatrics

Vol. 105, Issue 2

1 Feb 2000

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