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American Academy of Pediatrics
Article

Early Developmental Outcome After the Norwood Procedure for Hypoplastic Left Heart Syndrome

Jeffrey H. Kern, Veronica J. Hinton, Nancy E. Nereo, Constance J. Hayes and Welton M. Gersony
Pediatrics November 1998, 102 (5) 1148-1152; DOI: https://doi.org/10.1542/peds.102.5.1148
Jeffrey H. Kern
From the *Columbia–Presbyterian Medical Center, Department of Pediatrics; and the
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Veronica J. Hinton
‡GH Sergievsky Center and Department of Neurology, Columbia University College of Physicians and Surgeons, New York, New York.
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Nancy E. Nereo
‡GH Sergievsky Center and Department of Neurology, Columbia University College of Physicians and Surgeons, New York, New York.
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Constance J. Hayes
From the *Columbia–Presbyterian Medical Center, Department of Pediatrics; and the
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Welton M. Gersony
From the *Columbia–Presbyterian Medical Center, Department of Pediatrics; and the
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Abstract

Objective. To assess intellect and adaptive behavior in children with hypoplastic left heart syndrome (HLHS) who had undergone at least two surgical stages of the Norwood procedure.

Methods. Fourteen children with HLHS >3 years of age participated in the study. The patients underwent intelligence quotient (IQ) testing, and their parents were interviewed regarding their children's adaptive behavior. Results were compared with those of 10 family controls. Outcomes were studied for possible correlation with perioperative variables.

Results. Among the HLHS patients, the median scores for full scale IQ and adaptive behavior were 88 and 91, respectively (normal = 100 ± 15). One child met criteria for mental retardation. Family controls scored generally higher than did HLHS patients, but only differences in adaptive behavior were statistically significant. A negative correlation was found between stage I circulatory arrest time and full scale IQ.

Conclusions. Children with HLHS most often function in the low-normal range of intelligence and adaptive behavior. A prolonged circulatory arrest time may result in decreased intellectual function.

  • congenital heart disease
  • cardiac surgery
  • neurodevelopment
  • Received February 3, 1998.
  • Accepted April 23, 1998.
  • Copyright © 1998 American Academy of Pediatrics

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Pediatrics
Vol. 102, Issue 5
1 Nov 1998
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Early Developmental Outcome After the Norwood Procedure for Hypoplastic Left Heart Syndrome
Jeffrey H. Kern, Veronica J. Hinton, Nancy E. Nereo, Constance J. Hayes, Welton M. Gersony
Pediatrics Nov 1998, 102 (5) 1148-1152; DOI: 10.1542/peds.102.5.1148

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Early Developmental Outcome After the Norwood Procedure for Hypoplastic Left Heart Syndrome
Jeffrey H. Kern, Veronica J. Hinton, Nancy E. Nereo, Constance J. Hayes, Welton M. Gersony
Pediatrics Nov 1998, 102 (5) 1148-1152; DOI: 10.1542/peds.102.5.1148
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  • A Systematic Review of Motor and Cognitive Outcomes After Early Surgery for Congenital Heart Disease
  • Two-Year Survival and Mental and Psychomotor Outcomes After the Norwood Procedure: An Analysis of the Modified Blalock-Taussig Shunt and Right Ventricle-to-Pulmonary Artery Shunt Surgical Eras
  • Relationship of Surgical Approach to Neurodevelopmental Outcomes in Hypoplastic Left Heart Syndrome
  • Management of Infants With Hypoplastic Left Heart Syndrome: Integrating Research Into Nursing Practice
  • Clinical Outcomes and Secondary Diagnoses for Infants Born With Hypoplastic Left Heart Syndrome
  • Functional Limitations in Young Children With Congenital Heart Defects After Cardiac Surgery
  • Allopurinol Neurocardiac Protection Trial in Infants Undergoing Heart Surgery Using Deep Hypothermic Circulatory Arrest
  • Impact of Prenatal Diagnosis on Survival and Early Neurologic Morbidity in Neonates With the Hypoplastic Left Heart Syndrome
  • Cognitive Development After the Fontan Operation
  • Neurodevelopmental Outcome and Lifestyle Assessment in School-Aged and Adolescent Children With Hypoplastic Left Heart Syndrome
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