http://pediatrics.aappublications.org PEDIATRICS RSS feed -- recent REVIEW ARTICLES articles 1098-4275 PEDIATRICS 0031-4005 http://pediatrics.aappublications.org/icons/banner/title.gif http://pediatrics.aappublications.org http://pediatrics.aappublications.org/cgi/content/abstract/121/4/e975?rss=1 Although treatment of children and adolescents who have disorders of growth and adolescent development with aromatase inhibitors is increasingly common, data for or against their use are extremely limited. Precocious puberty, short stature, and gynecomastia are conditions for which inhibition of the enzyme aromatase might prove beneficial to reduce clinical signs of estrogenization and/or estrogen-mediated skeletal maturation. In this report, we summarize the published data regarding the use of aromatase inhibitors in these conditions, and review known and potential benefits, safety concerns, and shortcomings of the available information.

]]> 2008-04-01 info:doi/10.1542/peds.2007-2081 American Academy of Pediatrics 4 121 e983 2008-04-01 e975 REVIEW ARTICLES