TABLE 4

Stachybotrys Metabolites and Their Actions

Stachybotrys MetabolitesAction
AtranonesImmunotoxic, inflammatory
CyclosporinImmunosuppressive
EnzymesCollagenolytic proteinase
    Stachyrase A
HemolysinHemolytic
    Stachyhemolysin
Macrocyclic trichothecenesProtein synthesis inhibitors, cytotoxic
    Isosatratoxins
    Roridins
    Satratoxins
    Verrucarin
Microbial VOCsIrritant
    1-butanol
    3-methyl-1-butanol
    3-methyl-2-butanol thujopsene
PhenylspirodrimanesImmunosuppressive
    Spironolactones
    Spironolactams
Simple trichothecenesNot well defined
    Trichodermol
    Trichodermin
Trichoverroid trichothecenesaNot well defined
  • This table illustrates the many Stachybotrys mycotoxins and metabolites that may contribute to toxicity and is not meant to be comprehensive.

  • a Lie along the biosynthetic path between the simple and the macrocyclic trichothecenes.