TABLE 1

Status of Newborn Screening in the United States

StateCore ConditionsaAdditional Conditions Included in Screening Panel (Universally Required Unless Otherwise Indicated)
HearingEndocrineHemoglobinOther
HEARCHCAHHb S/SHb S/AHb S/CBIOGALTCF
AlabamaA
AlaskaA
ArizonaA
Arkansas
CaliforniaB5-OXO; HHH; PRO
Colorado
ConnecticutB5-OXO; HHH; HIVb; NKH
District of ColumbiaG6PD
DelawareA
FloridaC
GeorgiaA
Hawaii
IdahoA
Illinois5-OXO
Indiana
IowaHHH; NKH
Kansas
KentuckyACCC
Louisiana
MaineAHHH (A); CPS (D)
MarylandC
MassachusettsATOXO; HHH (A); CPS (D)
MichiganA
MinnesotaA
Mississippi5-OXO; CPS; HHH
MissouriCC
MontanaBBB
NebraskaA5-OXO; HHH; NKH (A)
NevadaA
New HampshireACCCCCCTOXO
New Jersey
New MexicoC
New YorkHIV
North Carolina
North DakotaA
Ohio
Oklahoma
OregonA
PennsylvaniaBB5-OXO; CPS; G6PD; HHH; NKH (B)
Rhode Island
South CarolinaA
South DakotaAB5-OXO; EMA; HHH; NKH
TennesseeA5-OXO; HHH; NKH
TexasA
Utah
VermontACPS
Virginia
WashingtonA
West Virginia
WisconsinA
Wyoming
  • A dot (•) indicates that screening for the condition is universally required by law or rule; A, universally offered but not yet required; B, offered to select populations or by request; C, testing required but not yet implemented; D, likely to be detected (and reported) as a byproduct of multiple reaction monitoring screening (MS/MS) targeted by law or rule. BIO indicates biotinidase; CAH, congenital adrenal hyperplasia; CF, cystic fibrosis; CH, congenital hypothyroidism; GALT, transferase-deficient galactosemia (classical); HBS/S, sickle cell disease; HB S/C, sickle C disease; HB S/A, S-β -thalassemia; HEAR, hearing screening; 5-OXO, 5-oxoprolinuria (pyroglutamic aciduria); CPS, carbamoylphosphate synthetase; EMA, ethylmalonic encephalopathy; G6PD, glucose 6 phosphate dehydrogenase; HHH, hyperammonemia/ornithinemia/citrullinemia (ornithine transporter defect); NKH, nonketotic hyperglycinemia; PRO, prolinemia; TOXO, toxoplasmosis.

  • a Terminology is consistent with that of the American College of Medical Genetics. Newborn Screening: Toward a Uniform Screening Panel and System. Rockville, MD: Health Resources and Services Administration; 2005:63.

  • b Newborn screened for HIV only if mother was not screened during pregnancy.