TABLE 2.

Neonatal and 6-Year Follow-up Characteristics of Children With Blood Pressure Follow-up Data at 6 Years of Age Available for Analysis Who Were Exposed Prenatally to Betamethasone or Placebo

Betamethasone*Placebo*Difference (95% CI)P
nParameternParameter
Neonatal variables
    Birth weight, g1212110 (1820 to 2620)1022295 (1950 to 2700)−170 (−320 to 0).05
    Birth weight z score121−0.36 (−0.92 to 0.1)102−0.35 (−0.78 to 0.23)−0.08 (−0.29 to 0.13).50
    Gestational age, d121241 (230 to 259)102245 (238 to 259)−6 (−11 to 0).08
    Entry/delivery interval, d1213.1 (1.1 to 27)1022.4 (1 to 31)0 (−0.7 to 0.5).99
    Term delivery12131 (25.6%)10228 (27.5%)0.93 (0.60 to 1.45).76
    Male12172 (59.5%)10256 (54.9%)1.08 (0.86 to 1.36).49
    RDS12110 (8.0%)10211 (10.8%)0.77 (0.34 to 1.73).52
    RDS (moderate or severe)1219 (7.4%)1029 (8.8%)0.84 (0.35 to 2.04).71
    5-min Apgar score of >712195 (78.5%)10277 (75.5%)1.04 (0.90 to 1.20).59
    Multiple pregnancy12116 (13.2%)10212 (11.8%)1.12 (0.56 to 2.26).74
    Instrumental delivery12159 (48.8%)10255 (53.9%)0.90 (0.70 to 1.17).44
6-year follow-up variables
    Age at follow-up, mo12175 (74 to 76)10274 (74 to 75)0 (0–1).34
    Height, cm119116.1 (112.5 to 120.1)102116.4 (112.7 to 120.0)−0.1 (−1.4 to 1.2).81
    Weight, kg11821.3 (19.5 to 23.4)10121 (19.6 to 23.3)0 (−0.7 to 0.7).78
    Head circumference, cm12152.1 (51.1 to 53)10251.9 (51 to 53)0.2 (−0.2 to 0.6).32
    Body mass index, kg/m211815.8 (15.0 to 16.7)10115.7 (14.9 to 16.6)0.1 (−0.2 to 0.4).73
    Low income§11919 (16.0%)10219 (18.6%)0.86 (0.48 to 1.53).11
    Maternal smoking11962 (52.1%)10251 (50.0%)1.04 (0.80 to 1.35).42
    Paternal smoking11965 (54.6%)10257 (55.9%)0.98 (0.77 to 1.24).60
    Age solids introduced (wk)9912 (8 to 16)9012 (8 to 16)2 (0 to 4).76
    Breastfed10125 (24.8%)9027 (30.0%)0.83 (0.52 to 1.31).85
  • * Data are either median (interquartile range) or count (percentage).

  • Data are either difference between medians (95% CI) or relative risk (95% CI).

  • Based on all live births in New Zealand, 1991/1992.15

  • § Household income of <$5000 (1976–1978 New Zealand dollars) or receiving state social welfare benefit.