TABLE 4.

Hib Vaccination Schedule and Risk of Type 1 Diabetes*

ScheduleCases N (%)Controls N (%)OR (95% CI)
Model 1**Model 2***
3 Doses by 8 mo plus 1 dose at 12–18 mo52 (27.2)135 (22.8)1.00 (referent)1.00 (referent)
1 Dose only at 21–27 mo8 (4.2)29 (4.9)0.59 (0.22–1.57)0.45 (0.15–1.30)
Other schedules123 (64.4)402 (67.8)0.69 (0.41–1.16)0.71 (0.41–1.24)
Not vaccinated8 (4.2)27 (4.6)0.68 (0.26–1.81)0.64 (0.22–1.81)
  • CI indicates confidence interval.

  • * Restricted to cases and controls ≥27 mo of age at incidence/index date.

  • ** Conditional logistic regression model stratified by matching variables (HMO, length of enrollment, gender, date of birth).

  • *** As in Model 1, plus adjusted for race/ethnicity and family history of possible type 1 diabetes.