TABLE 3.

Timing of Hepatitis B Vaccination and Risk of Type 1 Diabetes

Age at First VaccinationCases N (%)Controls N (%)OR (95% CI)
Model 1*Model 2**
Not vaccinated141 (56.0)412 (53.7)1.00 (referent)1.00 (referent)
0–14 d51 (20.2)168 (21.9)0.51 (0.23–1.15)0.66 (0.27–1.59)
15–55 d6 (2.4)24 (3.1)0.53 (0.18–1.52)0.65 (0.21–2.0)
≥56 d54 (21.4)164 (21.4)0.86 (0.54–1.35)0.74 (0.45–1.21)
  • CI indicates confidence interval.

  • * Conditional logistic regression model stratified by matching variables (HMO, length of enrollment, gender, date of birth).

  • ** As in Model 1, plus adjusted for race/ethnicity and family history of possible type 1 diabetes.