TABLE 2.

Association Between Childhood Vaccines and Type 1 Diabetes

VaccineVaccinatedOR (95% CI)
Cases N (%)Controls N (%)Model 1*Model 2**
Hepatitis B111 (44.0)356 (46.4)0.81 (0.52–1.27)0.73 (0.45–1.19)
Hib241 (95.6)729 (94.9)1.14 (0.51–2.57)1.23 (0.53–2.89)
Pertussis (whole cell)242 (96.0)748 (97.4)0.28 (0.07–1.06)0.23 (0.06–0.93)
Pertussis (acellular)58 (23.0)177 (23.0)0.92 (0.53–1.57)1.12 (0.63–1.99)
MMR232 (92.1)696 (90.6)1.36 (0.70–2.63)1.43 (0.71–2.86)
Varicella40 (15.9)112 (14.6)1.16 (0.72–1.89)1.02 (0.61–1.72)
  • CI indicates confidence interval.

  • * Conditional logistic regression model stratified by matching variables (HMO, length of enrollment, gender, date of birth).

  • ** As in Model 1, plus adjusted for race/ethnicity and family history of possible type 1 diabetes.