Table 3.

Presence and Duration of Symptoms in Household Contacts of Children With Culture-proven Pertussis by Treatment Group

SymptomNumber (%) Reporting SymptomMean Duration (Days) of Symptoms
ErythromycinPlaceboPValueErythromycinPlaceboP Value
Any symptom98  (68.1)127  (76.5).1461.846.6.87
Nasal congestion83  (57.6)93  (56.0).8639.140.2.96
Any cough88  (61.1)110  (66.3).4553.846.4.25
 Worse at night50  (34.7)70  (42.2).3238.638.87
 Paroxysmal31  (21.5)41  (24.7).5537.150.5.17
 With vomiting13  (9.0)31  (18.7).03* 24.828.5.71
Whoop10  (6.9)22  (13.3).0834.921.46
Apnea1  (0.7)4  (2.4).2819.3.71
Cyanosis1  (0.7)1  (0.6).917915.32
  • * Statistically significant; P < .05.