TABLE 1

Frequencies, IRs, and APC in SEER 9 for Childhood and Adolescent Melanoma From 1973 Through 2009

CategoryNo. (%)IRa (95% CI)APCb,c (95% CI)
Overall1230 (100)6.0 (5.7–6.3)2.0% (1.4 to 2.7)*
Gender
 Male483 (39)4.6 (4.2–5.0)1.9% (1.1 to 2.6)*
 Female747 (61)7.4 (6.9–8.0)2.2% (1.4 to 3.1)*
Age at diagnosis
 0–9 y104 (8)1.1 (0.9–1.3)2.5% (–0.4 to 5.4)
 10–14 y184 (15)3.6 (3.1–4.2)2.9% (1.0 to 4.7)*
 15–19 y942 (77)18.0 (16.9–19.2)1.9% (1.2 to 2.5)*
Stage at diagnosis
 Localizedd949 (77)4.6 (4.3–4.9)4.3% (0.5 to 8.2)e*
0.9% (–1.8 to 3.5)f
 Regional155 (13)0.8 (0.6–0.9)5.9% (2.7 to 9.2)*
 Distant28 (2)0.1 (0.1–0.2)0.8% (–7.1 to 9.3)
 Unstaged98 (8)0.5 (0.4–0.6)–4.0% (–6.5% to 1.3)*
Primary site
All sitesg1230 (100)6.0 (5.7–6.3)2.1% (1.4 to 2.8)*
 C44.2: External ear27 (2)0.1 (0.1–0.2)−2.0% (–8.0 to 4.4)
 C44.3: Skin of other/unspecified parts of face83 (7)0.4 (0.3–0.5)4.5% (0.7 to 8.4)*
 C44.4: Skin of scalp and neck102 (8)0.5 (0.4–0.6)0.8% (–1.8 to 3.4)
 C44.5: Skin of trunk436 (35)2.1 (1.9–2.3)2.8% (1.2 to 4.5)*
 C44.6: Skin of upper limb and shoulder224 (18)1.1 (1.0–1.2)0.6% (–1.4 to 2.7)
 C44.7: Skin of lower limb and hip273 (22)1.3 (1.2–1.5)2.6% (1.7 to 3.5)*
 C44.9: Skin, NOS30 (2)0.1 (0.1–0.2)1.7% (–2.1 to 5.7)
 C69.0: Conjunctiva7 (1)0.0 (0.0–0.1)−1.1% (–4.4 to 2.3)
 C69.3: Choroid11 (1)0.1 (0.0–0.1)2.4% (–2.9 to 8.0)
 C69.4: Ciliary body18 (1)0.1 (0.1–0.1)−5.3% (–11.9 to 1.8)
UV–B exposure
 Low688 (56)5.5 (5.1–6.0)3.7% (2.6 to 4.7)*
 High542 (44)6.7 (6.2–7.3)0.3% (−1.1 to 1.8)
  • Data are for 1973 through 2009 except as noted. NOS, not otherwise specified.

  • a IR indicates age-adjusted IR.

  • b APCs analyzed using 5-y intervals due to small numbers (1973–1977, 1978–1982, 1983–1987, 1988–1992, 1993–1997, 1998–2002, 2003–2009).

  • c APC was calculated via weighted least-squares regression.

  • d Best fit model contained 1 joinpoint. APC (0 joinpoint), 2.3%; 95% CI, 1.2–3.4 (significant).

  • e Years 1973–1990.

  • f Years 1990–2009.

  • g Sites with ≤5 cases were excluded from IR and APC analysis (n = 19).

  • * Indicates statistical significance at the .05 level.