TABLE 4

Estimated Tdap VE Against Pertussis, by Brand and Vaccine Group

CasesControlsOdds Ratio (95% CI)Estimated VE (95% CI), %
All birth years
 n8362322
 Tdap-unvaccinated162229ReferenceReference
 Boostrix38712450.40 (0.30 to 0.52)60.1 (47.7 to 69.6)
 Adacel1363420.51 (0.37 to 0.71)48.8 (28.8 to 63.2)
 Unknown brand1515060.37 (0.27 to 0.50)63.2 (49.9 to 73.0)
Acellular vaccine group (birth years 1998–2000)
 n4501256
 Tdap-unvaccinated109154ReferenceReference
 Boostrix2317250.37 (0.27 to 0.53)62.6 (47.4 to 73.4)
 Adacel501290.44 (0.28 to 0.71)55.7 (29.3 to 72.2)
 Unknown brand602380.27 (0.17 to 0.42)73.3 (58.5 to 82.8)
Mixed-vaccine group (birth years 1993–1997)
 n3861076
 Tdap-unvaccinated5375ReferenceReference
 Boostrix1565200.44 (0.28 to 0.68)56.5 (31.7 to 72.3)
 Adacel862130.61 (0.37 to 0.99)39.2 (0.04 to 62.8)
 Unknown brand912680.49 (0.31 to 0.78)50.6 (22.2 to 68.7)