TABLE 5

Drugs Used in the Treatment of Neonatal Narcotic Withdrawal

DrugInitial DoseIncrementMaximum DoseRef. No.
Oral morphine0.04 mg/kg every 3–4 h0.04 mg/kg per dose0.2 mg/kg per dose119,121,126,133
Oral methadone0.05–0.1 mg/kg every 6 h0.05 mg/kg per doseTo effect127
Oral clonidine0.5–1 µg/kg every 3–6 hNot studied1 µg/kg every 3 h132–135