TABLE 2

Associations Between Age at Introduction of Solid Foods During First Year of Life and Sensitization to Food and Inhalant Allergens in Children 5 Years of Age

Age at Introduction of FoodsaAll, n (%) (N = 994)Odds Ratio (95% Confidence Interval)
Any Food AllergenAny Inhalant Allergen
UnadjustedAdjustedbUnadjustedAdjustedb
Exclusive breastfeeding
    <0.92 mo330 (33)1.001.001.001.00
    0.92–3.00 mo357 (36)1.18 (0.78–1.79)1.29 (0.80–2.10)0.83 (0.58–1.19)0.84 (0.55–1.28)
    >3.00 mo307 (31)1.33 (0.87–2.02)1.61 (0.98–2.65)1.29 (0.90–1.84)1.30 (0.85–1.98)
    Pc.415.167.053.118
Total breastfeeding
    <5.00 mo306 (31)1.001.001.001.00
    5.00–9.00 mo370 (37)1.07 (0.71–1.61)1.40 (0.86–2.29)1.01 (0.71–1.44)1.19 (0.78–1.81)
    >9.00 mo318 (32)0.96 (0.62–1.47)1.07 (0.63–1.83)0.86 (0.60–1.26)0.69 (0.43–1.11)
    Pc.854.317.666.030
Cow's milk
    <0.93 mo333 (33)1.001.001.001.00
    0.93–4.00 mo337 (34)1.09 (0.72–1.65)1.25 (0.77–2.03)0.91 (0.63–1.32)0.85 (0.55–1.29)
    >4.00 mo334 (33)1.20 (0.80–1.81)1.51 (0.93–2.46)1.24 (0.87–1.76)1.40 (0.92–2.12)
    Pc.675.247.223.059
Potatoes
    <3.10 mo346 (35)1.001.001.001.00
    3.10–4.00 mo432 (43)1.12 (0.75–1.67)1.50 (0.93–2.42)1.31 (0.93–1.85)1.30 (0.86–1.95)
    >4.00 mo216 (22)1.74 (1.12–2.70)d2.56 (1.49–4.39)e1.67 (1.13–2.48)d1.93 (1.20–3.11)e
    Pc.032.003.037.025
Fruits and berries
    <3.46 mo266 (27)1.001.001.001.00
    3.46–4.00 mo405 (41)1.08 (0.70–1.66)1.30 (0.78–2.16)1.01 (0.70–1.47)1.09 (0.70–1.69)
    >4.00 mo323 (32)1.41 (0.91–2.19)1.70 (1.00–2.90)1.30 (0.89–1.91)1.54 (0.97–2.45)
    Pc.221.143.257.121
Carrots
    <3.50 mo279 (28)1.001.001.001.00
    3.50–4.00 mo417 (42)0.98 (0.65–1.49)1.15 (0.70–1.90)1.09 (0.76–1.57)1.02 (0.66–1.57)
    >4.00 mo298 (30)1.26 (0.82–1.95)1.66 (0.97–2.83)1.29 (0.88–1.90)1.37 (0.86–2.18)
    Pc.394.134.394.282
Cabbages
    <4.10 mo346 (35)1.001.001.001.00
    4.10–5.20 mo284 (29)1.02 (0.66–1.58)1.00 (0.61–1.65)1.05 (0.73–1.51)1.00 (0.66–1.52)
    >5.20 mo364 (36)1.27 (0.85–1.88)1.51 (0.94–2.42)0.81 (0.57–1.15)0.86 (0.56–1.30)
    Pc.427.141.317.704
Oats
    <5.00 mo156 (16)1.001.001.001.00
    5.00–5.50 mo566 (57)0.76 (0.47–1.23)0.85 (0.48–1.52)0.75 (0.50–1.13)0.71 (0.43–1.15)
    >5.50 mo272 (27)1.61 (0.98–2.67)1.82 (0.99–3.37)1.08 (0.69–1.68)1.20 (0.71–2.05)
    Pc<.001.002.077.021
Wheat
    <5.00 mo339 (34)1.001.001.001.00
    5.00–6.00 mo295 (30)0.92 (0.59–1.43)0.97 (0.58–1.61)0.96 (0.66–1.41)0.89 (0.57–1.38)
    >6.00 mo360 (36)1.45 (0.98–2.14)1.49 (0.93–2.37)1.33 (0.94–1.88)1.42 (0.94–2.15)
    Pc.059.127.137.066
Rye
    <5.60 mo331 (33)1.001.001.001.00
    5.60–7.00 mo353 (36)1.19 (0.77–1.85)1.23 (0.74–2.03)1.03 (0.71–1.48)1.06 (0.69–1.61)
    >7.00 mo310 (31)2.07 (1.36–3.14)e2.30 (1.40–3.75)e1.48 (1.03–2.12)d1.62 (1.06–2.49)d
    Pc.001.002.057.047
Meat
    <5.10 mo522 (52)1.001.001.001.00
    5.10–5.50 mo167 (17)0.88 (0.54–1.46)0.82 (0.46–1.48)0.78 (0.50–1.22)0.80 (0.48–1.33)
    >5.50 mo305 (31)1.35 (0.94–1.95)1.65 (1.07–2.55)d1.38 (1.00–1.91)d1.64 (1.12–2.41)d
    Pc.164.027.031.010
Fish
    <6.10 mo337 (34)1.001.001.001.00
    6.10–8.20 mo297 (30)1.12 (0.71–1.77)1.50 (0.89–2.53)0.78 (0.53–1.16)0.81 (0.53–1.26)
    >8.20 mo360 (36)1.90 (1.27–2.84)d2.42 (1.48–3.95)e1.40 (0.99–1.97)1.51 (1.00–2.28)d
    Pc.003.002.007.015
Eggs
    <8.10 mo269 (27)1.001.001.001.00
    8.10–10.50 mo329 (33)1.16 (0.71–1.87)1.04 (0.60–1.80)1.09 (0.74–1.62)1.03 (0.66–1.62)
    >10.50 mo396 (40)2.05 (1.33–3.17)e2.02 (1.23–3.32)e1.47 (1.02–2.13)d1.49 (0.98–2.27)
    Pc.001.002.075.093
  • a Age at introduction of solid foods categorized in thirds.

  • b Adjusted for season of birth, place of birth, gender, number of siblings, parental asthma, parental allergic rhinitis, maternal age, maternal basic education, maternal smoking during pregnancy, mode of delivery, pets at home during the first year, and ponderal index.

  • c Overall P values.

  • d P < .05.

  • e P < .01.