TABLE 15

Key Action Statement 3D: Clinicians should evaluate patients for and educate caregivers about potential adverse effects of propranolol, including sleep disturbances, bronchial irritation, and clinically symptomatic bradycardia and hypotension (grade X, strong recommendation).

Aggregate Evidence QualityGrade X
BenefitsRecognition of adverse effects of propranolol treatment
Risks, harm, costRisk of caregivers declining medical therapy because of concern about potential adverse effects
Benefit-harm assessmentBenefits outweigh harms
Intentional vaguenessNone
Role of patient preferenceNone
ExclusionsNone
StrengthStrong recommendation
Key references3,46,61,76,80,8588