TABLE 1

Onset, Duration, and Frequency of NAS Caused by Various Substances

DrugOnset, hFrequency, %Duration, d
Opioids
 Heroin24‒48 40‒80278‒10
 Methadone48‒72 13‒9437Up to 30 or more
 Buprenorphine36‒60 22‒6746,48Up to 28 or more
 Prescription opioid medications36‒72 5‒2056,6010‒30
Nonopioids
 SSRIs24‒48 20‒30642‒6
 TCAs24‒48 20‒50642‒6
 Methamphetamines24 2‒491017‒10
 Inhalants24‒48 48702‒7