TABLE 4

Prevalence of Hospitalization for Mental Health Diagnoses in TGNC Children Ages 10–17 Years Relative to Those in Referent Groups

Categories of Mental Health DisordersPrevalence in Transfeminine Subjects, N (%)PR (95% CI)a in Transfeminine SubjectsPrevalence in Transmasculine Subjects, N (%)PR (95% CI)a in Transmasculine Subjects
Versus Reference MalesVersus Reference FemalesVersus Reference MalesVersus Reference Females
All diagnoses of interest
 Ever before index date58 (13.6)9.9 (6.9–14.0)8.9 (6.3–12.5)99 (15.1)10.2 (7.8–13.3)7.8 (6.1–10.0)
 6 mo before index date33 (7.7)43.9 (19.7–110.7)35.1 (16.7–80.4)59 (9.0)35.3 (20.4–64.1)21.9 (13.7–35.8)
Anxiety disorders
 Ever before index date9 (2.1)9.0 (3.2–24.9)6.0 (2.3–14.8)25 (3.8)15.0 (7.7–29.8)13.4 (7.1–26.0)
 6 mo before index date6 (1.4)59.8 (7.2–2757.2)29.9 (5.3–303.7)13 (2.0)43.4 (11.9–238.3)32.6 (10.0–137.8)
Attention deficit disorders
 Ever before index date20 (4.7)9.8 (5.0–19.1)14.7 (7.0–31.7)14 (2.1)4.0 (2.0–7.7)9.4 (4.2–20.9)
 6 mo before index date6 (1.4)19.9 (4.2–123.6)59.8 (7.2–2755.8)bc9.9 (1.3–74.0)
Autism spectrum disorders
 Ever before index dateb6.6 (1.4–28.0)39.7 (3.9–1957.7)5 (0.8)5.0 (1.3–16.0)8.3 (2.0–32.6)
 6 mo before index datebccb3.3 (0.1–41.0)c
Bipolar disorders
 Ever before index date12 (2.8)30.3 (9.1–129.6)13.5 (5.2–36.4)18 (2.8)10.1 (4.9–20.7)9.1 (4.5–18.2)
 6 mo before index dateb39.7 (3.9–1958.7)19.8 (2.8–219.9)8 (1.2)15.9 (4.6–62.0)19.9 (5.3–90.7)
Conduct and/or disruptive disorders
 Ever before index date10 (2.3)16.8 (5.5–56.4)16.8 (5.5–56.4)10 (1.5)5.9 (2.4–13.6)6.7 (2.7–15.9)
 6 mo before index date5 (1.2)49.7 (5.5–2357.0)cb39.6 (3.9–1951.1)39.6 (3.9–1954.4)
Depressive disorders
 Ever before index date41 (9.6)21.1 (12.1–38.1)10.3 (6.4–16.4)83 (12.7)17.8 (12.5–25.2)9.1 (6.8–12.1)
 6 mo before index date26 (6.1)68.0 (23.4–269.3)54.3 (20.4–182.2)49 (7.5)104.0 (41.5–335.9)21.7 (12.9–37.2)
Eating disorders
 Ever before index dateb6.6 (0.5–57.7)2.8 (0.3–14.9)6 (0.9)29.8 (5.3–302.1)4.0 (1.3–10.9)
 6 mo before index datebc3.3 (0.1–41.0)b29.8 (5.3–302.1)4.0 (1.3–10.9)
Psychoses
 Ever before index date8 (1.9)26.7 (6.4–156.9)11.4 (3.6–37.2)10 (1.5)20.0 (6.2–74.7)12.5 (4.4–36.6)
 6 mo before index date5 (1.2)49.7 (5.5–2357.0)49.7 (5.5–2355.8)b19.8 (2.8–219.1)9.9 (1.8–53.3)
Personality disorders
 Ever before index dateb39.7 (3.9–1958.7)19.8 (2.8–219.9)8 (1.2)26.5 (6.3–155.7)8.9 (3.0–26.0)
 6 mo before index date0 (0)NCNC7 (1.1)c69.7 (8.9–3144.6)
Schizophrenia spectrum disorders
 Ever before index datebc14.8 (1.7–178.2)b9.9 (1.8–53.2)13.2 (2.2–90.4)
 6 mo before index date0 (0)NCNCb9.9 (0.1–773.9)9.9 (0.1–775.2)
Self-inflicted injuries
 Ever before index dateb6.6 (0.5–57.7)4.9 (0.4–34.6)13 (2.0)65.2 (14.7–596.2)13.0 (5.3–33.4)
 6 mo before index datebcc7 (1.1)c34.8 (6.6–344.4)
Substance use disorders
 Ever before index date8 (1.9)5.7 (2.1–14.7)4.2 (1.6–10.1)16 (2.4)6.2 (3.1–12.0)6.2 (3.1–12.1)
 6 mo before index date6 (1.4)29.9 (5.3–303.9)12.0 (3.0–49.7)9 (1.4)11.2 (3.8–33.5)11.2 (3.8–33.6)
Suicidal ideation
 Ever before index date9 (2.1)15.1 (4.8–51.7)5.6 (2.2–13.6)29 (4.4)19.8 (10.2–40.1)11.5 (6.5–20.4)
 6 mo before index date7 (1.6)c23.3 (5.3–140.2)17 (2.6)24.5 (9.6–70.1)21.5 (8.7–57.7)
  • NC, not calculated because there were 0 cases among transgender subjects.

  • a Logistic regression with exact 95% CIs for rare events (prevalence ≤10% in both the transgender and referent cohorts) or logistic regression with log link and approximate 95% CIs for not-rare events (>10% prevalence in either the transgender or referent cohorts).

  • b Fewer than 5 cases were not reported.

  • c Not calculated because there were 0 cases among referents.