TABLE 2

Prevalence of Mental Health Diagnoses in TGNC Children Ages 3–9 Years Relative to Those in Referent Groups

Categories of Mental Health DisordersPrevalence in Transfeminine Subjects, N (%)PR (95% CI)a in Transfeminine SubjectsPrevalence in Transmasculine Subjects, N (%)PR (95% CI)a in Transmasculine Subjects
Versus Reference MalesVersus Reference FemalesVersus Reference MalesVersus Reference Females
All diagnoses of interest
 Ever before index date51 (31.7)3.0 (2.3–3.9)5.7 (4.2–7.7)31 (34.4)3.3 (2.3–4.6)5.4 (3.7–7.8)
 6 mo before index date46 (28.6)6.0 (4.3–8.4)13.0 (8.7–19.6)26 (28.9)5.9 (3.8–9.0)10.7 (6.4–17.8)
Anxiety disorders
 Ever before index date19 (11.8)4.4 (2.6–7.4)6.3 (3.6–10.9)14 (15.6)6.3 (3.3–11.9)6.0 (3.2–11.3)
 6 mo before index date15 (9.3)16.3 (6.7–41.4)23.3 (8.8–68.5)9 (10.0)9.8 (3.4–27.6)12.2 (4.0–37.3)
Attention deficit disorders
 Ever before index date24 (14.9)3.3 (2.1–5.0)6.1 (3.8–9.9)14 (15.6)2.8 (1.6–4.9)6.9 (3.6–13.2)
 6 mo before index date22 (13.7)5.0 (3.1–8.1)10.9 (6.1–19.6)14 (15.6)4.2 (2.3–7.6)12.6 (5.9–26.8)
Autism spectrum disorders
 Ever before index date8 (5.0)2.2 (0.9–4.9)11.8 (3.7–38.9)0NCNC
 6 mo before index date8 (5.0)3.9 (1.5–9.5)20.8 (5.5–95.3)0NCNC
Conduct and/or disruptive disorders
 Ever before index date12 (7.5)3.3 (1.5–6.7)14.2 (5.4–38.8)7 (7.8)6.2 (2.0–17.5)12.3 (3.5–45.5)
 6 mo before index date8 (5.0)8.3 (2.8–23.8)83.0 (11.0–3707.3)b13.7 (2.3–95.1)20.5 (2.9–229.2)
Depressive disorders
 Ever before index date9 (5.6)6.7 (2.5–17.0)7.8 (2.9–20.6)10 (11.1)27.5 (7.7–123.0)12.3 (5.0–30.5)
 6 mo before index date6 (3.7)8.8 (2.4–31.1)12.3 (3.1–51.5)8 (8.9)43.0 (8.4–422.3)28.5 (6.7–170.2)
Eating disorders
 Ever before index dateb3.7 (0.8–12.6)6.7 (1.4–28.8)0NCNC
 6 mo before index dateb10.0 (0.1–787.4)10.0 (0.1–784.0)0NCNC
  • NC, not calculated because there were 0 cases among transgender subjects.

  • a Logistic regression with exact 95% CIs for rare events (prevalence ≤10% in both the transgender and referent cohorts) or logistic regression with log link and approximate 95% CIs for not-rare events (>10% prevalence in either the transgender or referent cohorts).

  • b Fewer than 5 cases were not reported.