TABLE 2

Distribution of Genotypes for the Serotonin Transporter Gene (5-HTT) and Dopaminergic Pathway (N = 2420)

Gene or LocusVariant
5-HTTLPRLLLSSS
42%42%16%
STin210/1010/1212/12
10%40%50%
DRD2CCCTTT
45%42%13%
COMTVal/ValVal/MetMet/Met
38%48%14%
DRD44R/4R4R/7R7R/7R
55%37%8%
  • Less than 2% of the sample had rare genotypes not represented in Table 2. 5-HTTLPR, seratonin-transporter-linked polymorphic region; COMT, catechol-O-methyltransferase; DRD2, dopamine receptor D2; DRD4, dopamine receptor D4; STin2, a variable number of tandem repeats in intron 2 of the seratonin transporter.