TABLE 4

Prevalence of High-Risk Conditions and Influenza Vaccination Among Children With Influenza-Associated Death and Children in MarketScan Commercial Claims Database, 2010–2014

High-Risk CategoryaInfluenza-Associated Pediatric Deaths (N = 291)MarketScan Commercial Claims Data Set (N = 6 543 363)b
No.% TotalNo. (%) VaccinatedNo.% TotalNo. (%) Vaccinatedc
No high-risk conditiond1384728 (20)5 815 031891 557 855 (27)
Pulmonary conditions, including asthma391311 (28)414 8686175 528 (42)
Metabolic disorders622 (33)33 248<111 250 (34)
Neurologic disorders371311 (30)70 631124 627 (35)
Cardiac and congenital heart diseases1764 (24)45 448<116 367 (36)
Immunosuppressive conditions622 (33)58 094118 022 (31)
Pregnancye210 (0)18 523<16316 (34)
≥2 high-risk conditions46f1617 (37)83 146137 114 (45)
  • a Influenza-associated pediatric deaths and children from MarketScan database were classified into mutually exclusive high-risk categories based on groups at increased risk of complications, hospitalizations, or death due to influenza according to the ACIP; children with ≥2 high-risk conditions included those with conditions from ≥2 ACIP high-risk categories.

  • b Numbers and percentages for MarketScan Commercial Claims data set are averages over 4 influenza seasons, 2010–2011 through 2013–2014.

  • c Average over 4 influenza seasons of the number vaccinated by May of each season.

  • d Includes 3 deaths with unknown high-risk status.

  • e Pregnancy restricted to children aged 13–17 y.

  • f Among influenza-associated pediatric deaths, includes children with pulmonary conditions (n = 33), metabolic disorders (n = 12), neurologic disorders (n = 38), cardiac diseases (n = 13), and immunosuppressive conditions (n = 9).