TABLE 4

ROC for the NIAAA 2-Question Screen When Predicting DSM-5 Diagnoses by Middle and High School Participants

GroupPredict DSM-5 if NIAAA risk is:Sensitivity (95% CI)Specificity (95% CI)PPV (95% CI)NPV (95% CI)AUC
Middle school age group≥ Nondrinker1.00 (1.00–1.00)0.00 (0.00–0.00)0.00 (0.00–0.01)0.91
≥ Moderate risk0.89 (0.69–1.09)0.91 (0.90–0.92)0.05 (0.01–0.08)1.00 (1.00–1.00)
≥ High risk0.33 (0.02–0.63)0.99 (0.98–0.99)0.13 (0.00–0.27)1.00 (0.99–1.00)
> High risk0.00 (0.00–0.00)1.00 (1.00–1.00)1.00 (0.99–1.00)
High school age group≥ Nondrinker1.00 (1.00–1.00)0.00 (0.00–0.00)0.02 (0.02–0.03)0.90
≥ Lower risk0.97 (0.93–1.01)0.67 (0.65–0.69)0.07 (0.05–0.08)1.00 (1.00–1.00)
≥ Moderate risk0.88 (0.81–0.96)0.81 (0.80–0.82)0.10 (0.08–0.13)1.00 (0.99–1.00)
≥ High risk0.53 (0.41–0.65)0.95 (0.95–0.96)0.22 (0.16–0.28)0.99 (0.98–0.99)
> High risk0.00 (0.00–0.00)1.00 (1.00–1.00)0.98 (0.97–0.98)
  • AUC, area under the curve; NPV, negative predictive value; PPV, positive predictive value.