TABLE 4

HPV Prevalence Among Sexually Active Females Aged 14 to 24 Years, Overall and According to Vaccination History, NHANES 2003–2006 and 2009–2012

HPV Types/Vaccination HistoryPrevalence, % (95% CI)aPR (95% CI)
Prevaccine Era 2003–2006 (n = 1092)Vaccine Era 2009–2012 (n = 753a)Comparison of Vaccine Era With Prevaccine ErabComparison Within Vaccine Erac
Any HPV
 Overall54.4 (49.5–59.2)58.1 (52.9–63.1)1.00 (0.90–1.11)NA
 VaccinatedNA56.7 (50.6–62.6)1.01 (0.89–1.14)0.99 (0.85–1.15)
 UnvaccinatedNA59.5 (52.3–66.4)1.00 (0.87–1.16)Ref
Non-4vHPV HR
 Overall32.8 (28.9–37.0)38.0 (32.8–43.4)1.09 (0.93–1.28)NA
 VaccinatedNA37.2 (31.1–43.7)1.11 (0.91–1.34)0.98 (0.75–1.27)
 UnvaccinatedNA39.1 (31.6–47.1)1.10 (0.88–1.36)Ref
HPV-31, -33, and -45
 Overall6.6 (4.7–9.2)5.3 (3.7–7.6)0.76 (0.48–1.20)NA
 VaccinatedNA4.9 (2.9–8.1)0.74 (0.41–1.34)0.95 (0.50–1.83)
 UnvaccinatedNA5.8 (3.6–9.1)0.80 (0.46–1.37)Ref
HPV-31, -33, -45, -52, and -58
 Overall14.7 (11.8–18.1)13.1 (10.2–16.7)0.83 (0.60–1.15)NA
 VaccinatedNA14.3 (10.1–19.9)0.95 (0.64–1.42)1.22 (0.81–1.84)
 UnvaccinatedNA12.5 (9.2–16.8)0.76 (0.53–1.10)Ref
4vHPV
 Overall18.6 (16.1–21.3)10.8 (8.2–14.2)0.53 (0.40–0.71)NA
 VaccinatedNA2.1 (1.1–3.7)0.09 (0.05–0.18)0.11 (0.05–0.24)
 UnvaccinatedNA16.9 (12.3–22.6)0.83 (0.61–1.12)Ref
  • Non-4vHPV high-risk (HR) includes types -31, -33, -35, -39, -45, -51, -52, -56, -58, -59, -66, and -68. 4vHPV includes types -6, -11, -16, and -18. Vaccinated assessment was made by self-report or parent-reported receipt of at least 1 HPV vaccine dose. NA, not applicable.

  • a A total of 287 sexually active females were vaccinated (defined as a history of receipt of ≥1 vaccine dose), and 439 were unvaccinated. Data for 27 sexually active females who had no information on vaccination status are included in the overall group.

  • b Prevalence overall, among vaccinated and among unvaccinated in 2009–2012 compared with overall in 2003–2006, adjusted for race/ethnicity and number of lifetime sexual partners.

  • c Prevalence in vaccinated compared with unvaccinated in 2009–2012, adjusted for race/ethnicity and number of lifetime sexual partners.