We present a case of a boy who developed obsessive-compulsive disorder (OCD) shortly after an episode of acute disseminated encephalomyelitis (ADEM). To our knowledge, this is the first report of the development of OCD in a child who has had ADEM. This presentation is consistent with our understanding of OCD as a complex genetic disease involving the cerebral white matter tracts, and may indicate a potential pathway for the development of OCD in genetically vulnerable individuals or a shared trigger for the development of pediatric acute-onset neuropsychiatric syndrome and ADEM.
- ADEM —
- acute disseminated encephalomyelitis
- CSF —
- cerebrospinal fluid
- OCD —
- obsessive-compulsive disorder
- PANS —
- pediatric acute-onset neuropsychiatric syndrome
- Accepted May 10, 2013.
- Copyright © 2013 by the American Academy of Pediatrics