In the statement, "Universal Hepatitis B Immunization," by the Committee on Infectious Diseases (Pediatrics. 1992;89:795-800), the paragraph following the heading "Immunization of Infants Whose Mothers Have Unknown HBsAg Status" on page 797 should read:
An infant whose mother's HBsAg status is unknown and cannot be determined before delivery should be immunized at birth with the dose of vaccine recommended for infants of HBsAg-positive mothers (Table 1). The additional administration of HBIG should depend on the results of the serologic screening of the mother. The mother should be screened for HBsAg as soon as possible, since the efficacy of HBIG has been proven only when given within 12 hours of birth. If the mother is HBsAg-positive, HBIG should be administered immediately to the infant, provided that the infant is less than 1 week old. Efficacy of HBIG given 12 to 48 hours after birth is presumed, but unproven; its value when given between 48 hours and 7 days of age is not known. The HBsAg status of the mother also determines the subsequent vaccine dose and schedule, as previously described.
- Copyright © 1992 by the American Academy of Pediatrics