A 14-year-old female ingested 60 to 120 mg of nylidrin and 1 to 2 gm of chlorothiazide. She later developed chest pain, headache, flushing and shortness of breath. The initial heart rate was 156 and the blood pressure 125/0 mm Hg. The remainder of her physical examination was normal. Over six hours the diastolic pressure and heart rate returned to normal. The signs and symptoms were consistent with toxic effects of beta-receptor stimulation causing decreased peripheral vascular resistance, fall in end-diastolic blood pressure, and poor coronary perfusion.
- Copyright © 1974 by the American Academy of Pediatrics