Routine studies, for isolation and identification of the infectious agent, were made on patients showing signs of clinical encephalitis. The following results cover a period of about 10 years:
A strain of virus immunologically identical with the virus of St. Louis encephalitis was recovered from the peripheral blood. One of 81 attempts gave positive result, approximately 1%.
Seven strains of virus, comprising five of lymphocytic choriomeningitis, one of vaccinia and one of herpes simplex, were isolated from spinal fluid in 7 of 304 attempts, approximately 2%.
Increasing titer of type specific antibody to the virus of St. Louis encephalitis was demonstrated in 17 of 152 patients during the course of clinical encephalitis, approximately 1%.
- Received June 3, 1948.
- Copyright © 1949 by the American Academy of Pediatrics