August 2017, VOLUME 140 / ISSUE 2
Table of Contents
- Open AccessPredicting Risk of Serious Bacterial Infections in Febrile Children in the Emergency DepartmentAdam D. Irwin, Alison Grant, Rhian Williams, Ruwanthi Kolamunnage-Dona, Richard J. Drew, Stephane Paulus, Graham Jeffers, Kim Williams, Rachel Breen, Jennifer Preston, Duncan Appelbe, Christine Chesters, Paul Newland, Omnia Marzouk, Paul S. McNamara, Peter J. Diggle, Enitan D. CarrolPediatrics Aug 2017, 140 (2) e20162853; DOI: 10.1542/peds.2016-2853
Multinomial regression is used to model the risk of SBIs in febrile children in the ED.
- Open AccessProbiotics and Child Care Absence Due to Infections: A Randomized Controlled TrialRikke Pilmann Laursen, Anni Larnkjær, Christian Ritz, Hanne Hauger, Kim Fleischer Michaelsen, Christian MølgaardPediatrics Aug 2017, 140 (2) e20170735; DOI: 10.1542/peds.2017-0735
This is a randomized, placebo-controlled study in which we examine the effect of probiotics (BB-12 and LGG) on child care absenteeism and infections in infants.
- Open AccessAllergy Testing in Children With Low-Risk Penicillin Allergy SymptomsDavid Vyles, Juan Adams, Asriani Chiu, Pippa Simpson, Mark Nimmer, David C. BrousseauPediatrics Aug 2017, 140 (2) e20170471; DOI: 10.1542/peds.2017-0471
Our utilization of a penicillin allergy questionnaire identified children at low risk for true allergy who were subsequently tested and whose results were found to be negative.
- Open AccessPediatric Readmissions After Hospitalizations for Lower Respiratory InfectionsMari M. Nakamura, Alan M. Zaslavsky, Sara L. Toomey, Carter R. Petty, Maria C. Bryant, Alexandra T. Geanacopoulos, Ashish K. Jha, Mark A. SchusterPediatrics Aug 2017, 140 (2) e20160938; DOI: 10.1542/peds.2016-0938
Among Medicaid-insured children, readmissions after hospitalizations for LRIs vary across hospitals and sometimes seem to be related to the original hospitalization.
- Open AccessSpontaneous Closure of Patent Ductus Arteriosus in Infants ≤1500 gJana Semberova, Jan Sirc, Jan Miletin, Jachym Kucera, Ivan Berka, Sylva Sebkova, Sinead O’Sullivan, Orla Franklin, Zbynek StranakPediatrics Aug 2017, 140 (2) e20164258; DOI: 10.1542/peds.2016-4258
Spontaneous PDA closure in VLBW infants is extremely prevalent. Infants born <26 weeks and 750 g, respectively, have a significantly higher rate of PDA at hospital discharge.
- Open AccessImaging Strategies for Suspected Acute Cranial Shunt Failure: A Cost-Effectiveness AnalysisJay Pershad, Andrew Taylor, M. Kennedy Hall, Paul KlimoPediatrics Aug 2017, 140 (2) e20164263; DOI: 10.1542/peds.2016-4263
Comparative cost-effectiveness of cranial CT, fsMRI, and POCUS measurement of ONSD for acute shunt failure from the perspective of a health care organization.
- Open AccessPediatric ATV Injuries in a Statewide Sample: 2004 to 2014Mariano Garay, Joseph Hess, Douglas Armstrong, William HennrikusPediatrics Aug 2017, 140 (2) e20170945; DOI: 10.1542/peds.2017-0945
The incidence of ATV-related injuries decreased between 2009 and 2014. Mortality remained constant over an 11-year period. Children <16 years of age remain vulnerable to injuries.
- Open AccessBehavioral Risk Assessment From Newborn to Preschool: The Value of Older SiblingsMichelle Rodrigues, Noam Binnoon-Erez, Andre Plamondon, Jennifer M. JenkinsPediatrics Aug 2017, 140 (2) e20164279; DOI: 10.1542/peds.2016-4279
Interventions to improve developmental outcomes are most effective during preschool. A risk assessment for newborns with OSs shows fair prediction to school-entry child psychopathology.
- Open AccessIn-Hospital Quality-of-Care Measures for Pediatric Sepsis SyndromeFolafoluwa O. Odetola, Gary Freed, Caroline Shevrin, Brian Madden, Julie McCormick, Kevin DombkowskiPediatrics Aug 2017, 140 (2) e20170350; DOI: 10.1542/peds.2017-0350
Treatment of pediatric sepsis, a leading cause of child morbidity and mortality, is time sensitive. Measures of quality of in-hospital care might improve outcomes.
- Open AccessVariation in Preoperative Testing and Antireflux Surgery in InfantsHeather L. Short, Nikolay P. Braykov, James E. Bost, Mehul V. RavalPediatrics Aug 2017, 140 (2) e20170536; DOI: 10.1542/peds.2017-0536
By using the PHIS database, this study characterizes national variation in diagnostic testing and surgical utilization for infants with GERD.
- Open AccessEarly Hearing Detection and Vocabulary of Children With Hearing LossChristine Yoshinaga-Itano, Allison L. Sedey, Mallene Wiggin, Winnie ChungPediatrics Aug 2017, 140 (2) e20162964; DOI: 10.1542/peds.2016-2964
The benefits to vocabulary development of meeting current EHDI guidelines are documented in a large, multistate study.
- Open AccessBeverage Intake During Pregnancy and Childhood AdiposityMatthew W. Gillman, Sheryl L. Rifas-Shiman, Silvia Fernandez-Barres, Ken Kleinman, Elsie M. Taveras, Emily OkenPediatrics Aug 2017, 140 (2) e20170031; DOI: 10.1542/peds.2017-0031
In this study, we found that mothers who consumed more sugary beverages in midpregnancy had children with greater levels of adiposity.
- Open AccessInternational Variability in Gastrointestinal Decontamination With Acute PoisoningsSantiago Mintegi, Stuart R. Dalziel, Beatriz Azkunaga, Javier Prego, Eunate Arana-Arri, Yordana Acedo, Lorea Martinez-Indart, Javier Benito, Nathan Kuppermann, on behalf of the Pediatric Emergency Research Networks (PERN) Poisoning Working GroupPediatrics Aug 2017, 140 (2) e20170006; DOI: 10.1542/peds.2017-0006
This was an international, multicenter, cross-sectional prospective study of acute pediatric poisonings to assess the variation and appropriateness of GID in the ED.
- Open AccessAccuracy of Components of SCAT to Identify Children With ConcussionFranz E. Babl, Diana Dionisio, Lucy Davenport, Amy Baylis, Stephen J.C. Hearps, Silvia Bressan, Emma J. Thompson, Vicki Anderson, Ed Oakley, Gavin A. DavisPediatrics Aug 2017, 140 (2) e20163258; DOI: 10.1542/peds.2016-3258
SCATs are widely recommended and used. This study evaluates their use in children with concussion in the ED.
- Open AccessTrajectories of Motor Recovery in the First Year After Pediatric Arterial Ischemic StrokeAnna N. Cooper, Vicki Anderson, Stephen Hearps, Mardee Greenham, Michael Ditchfield, Lee Coleman, Rod W. Hunt, Mark T. Mackay, Paul Monagle, Anne L. GordonPediatrics Aug 2017, 140 (2) e20163870; DOI: 10.1542/peds.2016-3870
This study describes motor outcomes in the first year after pediatric stroke and the relationship between motor outcome and adaptive behavior.
- Open AccessCongenital Diaphragmatic Hernia and Growth to 12 YearsLisette Leeuwen, Daphne S. Mous, Joost van Rosmalen, Joanne F. Olieman, Laura Andriessen, Saskia J. Gischler, Koen F.M. Joosten, Rene M.H. Wijnen, Dick Tibboel, Hanneke IJsselstijn, Marjolein SpoelPediatrics Aug 2017, 140 (2) e20163659; DOI: 10.1542/peds.2016-3659
This prospective study reports longitudinal growth outcomes in 172 patients with CDH until 12 years of age.
- Open AccessSecular Trend of Age at Menarche in Chinese Adolescents Born From 1973 to 2004Xin Meng, Suyun Li, Wenhou Duan, Yanxin Sun, Chongqi JiaPediatrics Aug 2017, 140 (2) e20170085; DOI: 10.1542/peds.2017-0085
Through using a Chinese large data set from the CHNS, the authors of this study found a downward trend and investigated factors influencing age at menarche in Chinese girls born from 1973 to 2004.
- Open AccessFather Loss and Child Telomere LengthColter Mitchell, Sara McLanahan, Lisa Schneper, Irv Garfinkel, Jeanne Brooks-Gunn, Daniel NottermanPediatrics Aug 2017, 140 (2) e20163245; DOI: 10.1542/peds.2016-3245
This study of 2420 children reveals that separation from a father through death, incarceration, or separation and/or divorce is associated with accelerated telomere shortening in his children.
- Open AccessComparison of Recruitment Strategy Outcomes in the National Children’s StudyChristina H. Park, Marianne Winglee, Jennifer Kwan, Linda Andrews, Mark L. HudakPediatrics Aug 2017, 140 (2) e20162822; DOI: 10.1542/peds.2016-2822
Recruitment of pregnant women at obstetric provider offices and birth hospitals can enroll a nationally representative birth cohort with high efficiency and low cost.
- Open AccessSolving the Readmissions Puzzle: How Do Variability and Preventability Fit?Sowdhamini S. Wallace, Ricardo A. QuinonezPediatrics Aug 2017, 140 (2) e20171681; DOI: 10.1542/peds.2017-1681
From the American Academy of Pediatrics
- Open AccessThe Metabolic Syndrome in Children and Adolescents: Shifting the Focus to Cardiometabolic Risk Factor ClusteringSheela N. Magge, Elizabeth Goodman, Sarah C. Armstrong, COMMITTEE ON NUTRITION, SECTION ON ENDOCRINOLOGY, SECTION ON OBESITYPediatrics Aug 2017, 140 (2) e20171603; DOI: 10.1542/peds.2017-1603
- Open AccessOral and Dental Aspects of Child Abuse and NeglectSusan A. Fisher-Owens, James L. Lukefahr, Anupama Rao Tate, AMERICAN ACADEMY OF PEDIATRICS, SECTION ON ORAL HEALTH, COMMITTEE ON CHILD ABUSE AND NEGLECT, AMERICAN ACADEMY OF PEDIATRIC DENTISTRY, COUNCIL ON CLINICAL AFFAIRS, COUNCIL ON SCIENTIFIC AFFAIRS, AD HOC WORK GROUP ON CHILD ABUSE AND NEGLECTPediatrics Aug 2017, 140 (2) e20171487; DOI: 10.1542/peds.2017-1487
- Open AccessGuiding Principles for Team-Based Pediatric CareJulie P. Katkin, Susan J. Kressly, Anne R. Edwards, James M. Perrin, Colleen A. Kraft, Julia E. Richerson, Joel S. Tieder, Liz Wall, TASK FORCE ON PEDIATRIC PRACTICE CHANGEPediatrics Aug 2017, 140 (2) e20171489; DOI: 10.1542/peds.2017-1489
- Open AccessA New Approach to the Investigation of Sudden Unexpected DeathRichard D. Goldstein, Henry M. Nields, Hannah C. KinneyPediatrics Aug 2017, 140 (2) e20170024; DOI: 10.1542/peds.2017-0024
- Open AccessParental Management of Discharge Instructions: A Systematic ReviewAlexander F. Glick, Jonathan S. Farkas, Joseph Nicholson, Benard P. Dreyer, Melissa Fears, Christopher Bandera, Tanya Stolper, Nicole Gerber, H. Shonna YinPediatrics Aug 2017, 140 (2) e20164165; DOI: 10.1542/peds.2016-4165
This is a systematic review of the literature related to parental management (knowledge and execution) of inpatient and ED discharge instructions.
- Open AccessPromoting Early Child Development With Interventions in Health and Nutrition: A Systematic ReviewTyler Vaivada, Michelle F. Gaffey, Zulfiqar A. BhuttaPediatrics Aug 2017, 140 (2) e20164308; DOI: 10.1542/peds.2016-4308
This overview summarizes what is known about the impact of evidence-based health and nutrition interventions on early child development with a focus on low-resource settings.
- Open AccessVariations in Definitions and Outcome Measures in Gastroesophageal Reflux Disease: A Systematic ReviewMaartje M.J. Singendonk, Anna J. Brink, Nina F. Steutel, Faridi S. van Etten-Jamaludin, Michiel P. van Wijk, Marc A. Benninga, Merit M. TabbersPediatrics Aug 2017, 140 (2) e20164166; DOI: 10.1542/peds.2016-4166
Through systematic review, this study provides an overview of the definitions and outcome measures used in randomized controlled trials in pediatric GERD.
State-of-the-Art Review Article
- Open AccessPulmonary Alveolar Proteinosis: A Comprehensive Clinical PerspectiveMatthias GriesePediatrics Aug 2017, 140 (2) e20170610; DOI: 10.1542/peds.2017-0610
An age-dependent approach will differentiate PAP and inform about treatment and outcome.
- Open AccessMeasurement Challenges at Low Blood Lead LevelsKathleen L. Caldwell, Po-Yung Cheng, Jeffery M. Jarrett, Amir Makhmudov, Kathryn Vance, Cynthia D. Ward, Robert L. Jones, Mary E. MortensenPediatrics Aug 2017, 140 (2) e20170272; DOI: 10.1542/peds.2017-0272
This article aims to help pediatric health care professionals in understanding the measurement and clinical interpretation challenges of low blood lead measurements (<5 μg/dL).
- Open AccessCritical Issues in Food Allergy: A National Academies Consensus ReportScott H. Sicherer, Katrina Allen, Gideon Lack, Steve L. Taylor, Sharon M. Donovan, Maria OriaPediatrics Aug 2017, 140 (2) e20170194; DOI: 10.1542/peds.2017-0194
This article describes pediatric implications of the NAS report entitled “Finding a Path to Safety in Food Allergy: Assessment of the Global Burden, Causes, Prevention, Management, and Public Policy.”
- Open AccessResearch Priorities in Sudden Unexpected Infant Death: An International ConsensusFern R. Hauck, Betty L. McEntire, Leanne K. Raven, Francine L. Bates, Lucy A. Lyus, Alexis M. Willett, Peter S. BlairPediatrics Aug 2017, 140 (2) e20163514; DOI: 10.1542/peds.2016-3514
Via a multidisciplinary international consensus project, this study identifies the top 10 research priorities in SUID, aiming to reduce deaths globally.
- Open AccessPalliative Sedation With Propofol for an Adolescent With a DNR OrderLiza-Marie Johnson, Joel Frader, Joanne Wolfe, Justin N. Baker, Doralina L. Anghelescu, John D. LantosPediatrics Aug 2017, 140 (2) e20170487; DOI: 10.1542/peds.2017-0487
When a dying teenager is in intractable pain, is it ethically permissible to sedate with propofol, even if that may hasten death?
- Open AccessImproving Asthma Care by Building Statewide Quality Improvement InfrastructureJudith C. Dolins, Jennifer Powell, Edward Wise, Kimberly Giuliano, Peggy Stemmler, Wes Stubblefield, P. Cooper White, James Wiley, Dennis Z. KuoPediatrics Aug 2017, 140 (2) e20161612; DOI: 10.1542/peds.2016-1612
Improving asthma care by building statewide quality improvement infrastructure - a multiwave effort to drive wide scale improvement in pediatric asthma care.
- Open AccessInpatient-Derived Vital Sign Parameters Implementation: An Initiative to Decrease Alarm BurdenAlaina K. Kipps, Sarah F. Poole, Cheryl Slaney, Shannon Feehan, Christopher A. Longhurst, Paul J. Sharek, Veena V. GoelPediatrics Aug 2017, 140 (2) e20162458; DOI: 10.1542/peds.2016-2458
Implementation of data-driven, age-based HR parameters and iteratively derived RR parameters decreased cardiorespiratory alarms by 21% in a pediatric acute care unit.
- Open AccessControlling Phlebotomy Volume Diminishes PICU Transfusion: Implementation Processes and ImpactKatherine Steffen, Allan Doctor, Julie Hoerr, Jeff Gill, Chris Markham, Sarah M. Brown, Daniel Cohen, Rose Hansen, Emily Kryzer, Jessica Richards, Sara Small, Stacey Valentine, Jennifer L. York, Enola K. Proctor, Philip C. SpinellaPediatrics Aug 2017, 140 (2) e20162480; DOI: 10.1542/peds.2016-2480
Using implementation science, phlebotomy reduction strategies were used in a PICU to significantly reduce blood overdraw volumes and frequency of blood transfusion.
- Open AccessBenign Neonatal Shudders, Shivers, Jitteriness, or Tremors: Early Signs of Vitamin D DeficiencyMillicent Collins, Michal YoungPediatrics Aug 2017, 140 (2) e20160719; DOI: 10.1542/peds.2016-0719
This case report highlights the significance of mild, incidental shivering or jitteriness in the normal newborn, elucidating the role of vitamin D.
- Open AccessA Mercury Toxicity Case Complicated by Hyponatremia and Abnormal Endocrinological Test ResultsMatthew Carter, Abdul Abdi, Fareeha Naz, Farouq Thabet, Arpita VyasPediatrics Aug 2017, 140 (2) e20161402; DOI: 10.1542/peds.2016-1402
The convoluted clinical picture of Hg toxicity can render the diagnosis difficult, especially in the presence of hyponatremia and atypical endocrinological test results.
- Open AccessEarly Screening for Tetrahydrobiopterin Responsiveness in PhenylketonuriaFrancesco Porta, Marco Spada, Alberto PonzonePediatrics Aug 2017, 140 (2) e20161591; DOI: 10.1542/peds.2016-1591
Quantitative procedures to detect BH4 responsiveness in phenylketonuric infants were applied. Results raise more than the suspicion that patients considered “responsive” simply share milder genotypes and phenotypes.
- Open AccessA New Case of Congenital Malabsorptive Diarrhea and Diabetes Secondary to Mutant Neurogenin-3Marta Germán-Díaz, Yolanda Rodriguez-Gil, Jaime Cruz-Rojo, Fabienne Charbit-Henrion, Nadine Cerf-Bensussan, Javier Manzanares-López Manzanares, José Manuel Moreno-VillaresPediatrics Aug 2017, 140 (2) e20162210; DOI: 10.1542/peds.2016-2210
This case report describes a 16-year-old male patient with EA, a disorder characterized by congenital diarrhea secondary to a lack of ECs.
Letters to the Editors
- Open AccessAdolescent Bariatric Surgery and Thiamine Deficiency: What Do We Know So Far?Antonios Athanasiou, Michael Spartalis, Eleftherios SpartalisPediatrics Aug 2017, 140 (2) e20171633A; DOI: 10.1542/peds.2017-1633A