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    Pediatrics
    July 2016, VOLUME 138 / ISSUE 1
    Review Article

    Interventions to Improve HPV Vaccine Uptake: A Systematic Review

    Emily B. Walling, Nicole Benzoni, Jarrod Dornfeld, Rusha Bhandari, Bryan A. Sisk, Jane Garbutt, Graham Colditz
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    • TABLE 1

      Eligibility Criteria

      Inclusion
       Study design: any
       Participants: men and/or women 11–26 y old
       Intervention: to increase HPVV uptake
       Outcome: postintervention HPV vaccination rate reported
      Exclusion
       Postintervention HPV vaccination rates not reported
       No original data (exception made for articles describing government interventions)
       Abstract or research communication report only
       Population <11 or >26 y old
       Study not available in English
    • TABLE 2

      CGDA Intervention Categories

      CategoryIntervention Definition
      InformationalTo increase knowledge of HPV, HPV-related disease, or the HPVV
      BehavioralTo change behavior by providing necessary skills to make a decision regarding the HPVV.
      Subcategories by strategy: patient-targeted decision support (eg, message framing, health theory–based interventions), patient-targeted reminders, provider-targeted reminders, patient and provider interventions
      EnvironmentalTo change the social environment to facilitate vaccination, ie, decreased financial barriers, novel vaccination locations.
      Subcategory by policy level: small policy (organizational guidelines, no government involvement), large policy (formal laws, rules or regulations, national or local government involvement)
      • The authors determined the main category for interventions employing multiple strategies.

    • TABLE 3

      CGDA Intensity Level

      Intensity LevelExample
      Active engagement by stakeholders targeted toward the individualPatient or physician reminders
      Active engagement by stakeholders targeted to populationSchool-based VP, educational classes
      Passive engagement with significant effortEducational media campaigns
      Passive engagement with minimal effortNotice on Web site
      • Interventions using multiple methods were classified according to the method of the highest intensity.

    • TABLE 4

      RE-AIM Evaluation Dimensions

      Reach: proportion of the target population that participated in the intervention.
       Setting, population density, HPVV population, number of participants
      Efficacy: success rate if implemented as in guidelines
       Postintervention HPVV rates
      Adoption: proportion of settings, practices, and plans that will adopt this intervention
       If applicable, described with implementation
      Implementation: extent to which the intervention is implemented as intended
       Study design, barriers encountered
      Maintenance: extent to which a program is sustained over time
       Sustainability and acceptability of the intervention

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    Interventions to Improve HPV Vaccine Uptake: A Systematic Review
    Emily B. Walling, Nicole Benzoni, Jarrod Dornfeld, Rusha Bhandari, Bryan A. Sisk, Jane Garbutt, Graham Colditz
    Pediatrics Jul 2016, 138 (1) e20153863; DOI: 10.1542/peds.2015-3863

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    Interventions to Improve HPV Vaccine Uptake: A Systematic Review
    Emily B. Walling, Nicole Benzoni, Jarrod Dornfeld, Rusha Bhandari, Bryan A. Sisk, Jane Garbutt, Graham Colditz
    Pediatrics Jul 2016, 138 (1) e20153863; DOI: 10.1542/peds.2015-3863
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