Increased Prevalence of Familial Autoimmunity in Probands With Pervasive Developmental Disorders
Thayne L. Sweeten, Suzanne L. Bowyer, David J. Posey, Gary M. Halberstadt, Christopher J. McDougle

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Tables
- Table 2.
Mean Number of First- or Second-Degree Family Members With Autoimmune Disorders per Family and Number of Families in Each Group With a Specific Autoimmune Disorder*
PDD Autoimmune Healthy Mean Number per Family 1.87 ± 1.6†‡ 1.44 ± 1.5§ 0.93 ± 1.1 Hypothyroidism/ Hashimoto’s thyroiditis 36‖¶ 11 14 Rheumatic fever 23# 10 6 Multiple sclerosis 7 2 1 ↵* Each group consists of 101 families.
↵† Compared with autoimmune: t = 2.03; P = .03.
↵‡ Compared with healthy: t = 4.90; P = .000003.
↵§ Compared with healthy: t = 2.72; P = .01.
↵‖ Compared with autoimmune: χ2 = 18.06; P = .00002.
↵¶ Compared with healthy: χ2 = 13.21; P = .0003.
↵# Compared with healthy: χ2 = 12.31; P = .0005.
Increased Prevalence of Familial Autoimmunity in Probands With Pervasive Developmental Disorders
Thayne L. Sweeten, Suzanne L. Bowyer, David J. Posey, Gary M. Halberstadt, Christopher J. McDougle
Pediatrics Nov 2003, 112 (5) e420; DOI: 10.1542/peds.112.5.e420