Did you know? You can easily access AAP Policy Statements, Clinical Practice Guidelines, and Clinical and Technical Reports with the AAP Policy & Collections link in the black header bar above (or the 3-line menu button on a mobile device), or by clicking here.

The Transfer of Drugs and Other Chemicals Into Human Milk

Committee on Drugs
Table 7.

Food and Environmental Agents: Effects on Breastfeeding

AgentReported Sign or Symptom in Infant or Effect on LactationReference No.
AflatoxinNone354–356
AspartameCaution if mother or infant has phenylketonuria357
Bromide (photographic laboratory)Potential absorption and bromide transfer into milk; see Table 6 358
CadmiumNone reported359
ChlordaneNone reported360
Chocolate (theobromine)Irritability or increased bowel activity if excess amounts
(≥16 oz/d) consumed by mother
169, 361
DDT, benzene hexachlorides, dieldrin,
aldrin, hepatachlorepoxide
None362–370
Fava beansHemolysis in patient with G-6-PD deficiency371
FluoridesNone372, 373
HexachlorobenzeneSkin rash, diarrhea, vomiting, dark urine, neurotoxicity, death374, 375
HexachloropheneNone; possible contamination of milk from nipple washing376
LeadPossible neurotoxicity377–380
Mercury, methylmercuryMay affect neurodevelopment381–383
MethylmethacrylateNone384
Monosodium glutamateNone385
Polychlorinated biphenyls and
polybrominated biphenyls
Lack of endurance, hypotonia, sullen, expressionless facies386–390
SiliconeEsophageal dysmotility17–22
Tetrachloroethylene cleaning fluid
(perchloroethylene)
Obstructive jaundice, dark urine391
Vegetarian dietSigns of B12deficiency392