The Transfer of Drugs and Other Chemicals Into Human Milk

Committee on Drugs
Table 7.

Food and Environmental Agents: Effects on Breastfeeding

AgentReported Sign or Symptom in Infant or Effect on LactationReference No.
AspartameCaution if mother or infant has phenylketonuria357
Bromide (photographic laboratory)Potential absorption and bromide transfer into milk; see Table 6358
CadmiumNone reported359
ChlordaneNone reported360
Chocolate (theobromine)Irritability or increased bowel activity if excess amounts
(≥16 oz/d) consumed by mother
169, 361
DDT, benzene hexachlorides, dieldrin,
aldrin, hepatachlorepoxide
Fava beansHemolysis in patient with G-6-PD deficiency371
FluoridesNone372, 373
HexachlorobenzeneSkin rash, diarrhea, vomiting, dark urine, neurotoxicity, death374, 375
HexachloropheneNone; possible contamination of milk from nipple washing376
LeadPossible neurotoxicity377–380
Mercury, methylmercuryMay affect neurodevelopment381–383
Monosodium glutamateNone385
Polychlorinated biphenyls and
polybrominated biphenyls
Lack of endurance, hypotonia, sullen, expressionless facies386–390
SiliconeEsophageal dysmotility17–22
Tetrachloroethylene cleaning fluid
Obstructive jaundice, dark urine391
Vegetarian dietSigns of B12deficiency392