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Post-publication Peer Reviews to:

EXPERIENCE & REASON:
Mark N. Lobato, John A. Jereb, and Jeffrey R. Starke
Unintended Consequences: Mandatory Tuberculin Skin Testing and Severe Isoniazid Hepatotoxicity
Pediatrics 2008; 0: peds.2007-2773v1-1733 [Abstract] [Full text] [PDF]
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P3Rs published:

[Read P3R] investigate further
jayendra Gohil   (16 June 2008)

investigate further 16 June 2008
Top
jayendra Gohil,
Pediatrics faculty
medical college, Bhavnagar, india

Send letter to journal:
Re: investigate further

jayukids{at}yahoo.com jayendra Gohil

It should be decided by experts why Isoniazid is to be used ? As a single drug it can provide protection if a contact is sufffering from TB to prevent the child from getting infected. If contact has not been found and child is healthy she should be investigated to decide if she has active disease or not and if yes then fully treated. With positive Tuberculin test a source has to be found. And the drug needs to be discontinued in case of sideeffects.

Conflict of Interest:

None declared