To the Editor.
We read with great interest the article by Hellström et al regarding
that monitoring the early weight gain since birth predicts severe
retinopathy of prematurity (ROP).1 This aims to treat those babies with
laser retinal photocoagulation some weeks in advance and also minimize
unnecessary ophthalmological examinations in many newborns that nowadays
are routinely screened for ROP.
We agree that the use of weekly weight gain can predict ROP and/or
severe ROP that needs treatment. We also agree that it is a simple tool
very useful in developing countries, where survival rates of extremely-low
-birth-weight preterm infants are improving in recent years.2
Hellström et al included 354 patients born with gestational age (GA)
≤32 weeks, with a median GA of 30 weeks, and a median birth weight
(BW) of 1,310 g (range: 425-2,210 g). We recently published data from 317
patients screened for ROP in Brazil, where the median GA was 30 weeks, and
median BW was 1,155 g (range: 505-1,500 g). Hellström et al reported a
prevalence of stage 3 ROP of 9.9%, while our data showed 6.9% stage 3 ROP.
We demonstrated that a proportional weight gain over the birth weight at
six weeks of life below 51.2% was a good predictor of severe ROP.3 We
stress the need for simple tools without high costs to be used in the
middle-income countries.
We suggest that just monitoring the weight gain is an efficient way
to anticipate those at risk of severe ROP. We agree that the algorithm
proposed by Hellström et al is very useful, but must be validated among
other different population of preterm infants.
Sincerely yours
Joao Borges Fortes Filho M.D.
Renato S. Procianoy M.D.
Departments of Ophthalmology and Pediatrics, Newborn Section, School
of Medicine, Federal University of Rio Grande do Sul and Hospital de
Clinicas de Porto Alegre, Porto Alegre RS, Brazil.
References
1 Hellström A, Härd A, Engström E, Niklasson A, Andersson E, Smith L,
Löfqvist C. Early weight gain predicts retinopathy in preterm infants:
new, simple, efficient approach to screening. Pediatric 2009;123:e638-
e645.
2 Fortes Filho JB, Eckert GU, Procianoy L, Barros CK, Procianoy RS.
Incidence and risk factors for retinopathy of prematurity in very low and
in extremely low birth weight infants in a unit-based approach in southern
Brazil. Eye 2009;23(1):25-30.
3 Filho JB, Bonomo PP, Maia M, Procianoy RS. Weight gain measured at
6 weeks after birth as a predictor for severe retinopathy of prematurity:
study with 317 very low birth weight preterm babies. Graefes Arch Clin Exp
Ophthalmol 2008;DOI 10.1007/s00417-008-1012-3. Published online 04
December 2008.
Conflict of Interest:
None declared