We read with interest the article by O’Donnell and colleagues,
sincerely applaud their efforts and wholeheartedly agree: early
identification and intervention of drug use is of utmost importance,
especially for the affected children. This is not a purely Australian
issue; it applies to the U.S. and likely the globe. Drug abuse and
dependence are most prominent among women of childbearing age as are most
co-morbid mental illnesses such as major depression [1]. We strongly
advocate for preventive practices but believe that these alone will not
work and agree that accurate survey data on drug use is greatly needed.
Beyond this, part of the answer lies in drug testing of the mother,
especially within the setting of a prenatal exam. However, several
questions arise which has led to the issue largely being ignored: “If my
pregnant patient tests positive for drug use, doesn’t that leave me with
some responsibility to do something about it?, Who will pay for this
testing?, How can I fit this into my busy workday?” The authors began to
address some of this in their concluding that a multidisciplinary approach
to healthcare is required to tackle such complex issues. The significant
increase in the birth prevalence of neonatal withdrawal from ~1 to ~42 per
10,000 live births highlights the obvious increase in poorly treated or
untreated drug abuse/dependence and likely other comorbid mental illnesses
such as depression and bipolar disorder in the pregnant population. We
advise routine prenatal urine drug testing including tobacco (cotinine),
alcohol, codeine/morphine, amphetamine/methamphetamine, PCP, marijuana,
and cocaine that can all be done rapidly in the obstetrician’s office [2].
Testing should be performed at the first prenatal visit and particularly
when there are overt signs/symptoms of drug intoxication/abuse or other
high risk factors (e.g. family history) [3, 4, 5]. Drug testing may have
to be done at delivery as this may for some women with poor prenatal care
access be the only time to intervene. Reimbursement is now possible for
alcohol/drug screening and brief office-based interventions thus reducing
payment issues [6].
Positive testing should lead to early education, support, and
referral for treatment. The involvement of pre/post-natal care teams that
include addiction medicine physicians and psychiatrists with expertise in
the evaluation and treatment of addiction and psychiatric disorders during
pregnancy is highly recommended as there is likely no more complicated
case than a pregnant woman with bipolar disorder or psychosis who is
addicted to cocaine (for example). The education of psychiatry resident
and addiction medicine fellow trainees should focus more on this critical
period as it affects not only the mother but also the infant/child for
possibly many years, and the use of psychoactive medications during
pregnancy requires specialized knowledge of risks to the fetus and an
overall understanding of the physiological/hormonal changes that accompany
pregnancy and postpartum that alter drug metabolism and risk of
psychiatric illness.
REFERENCES
1. Blehar MC. Public health context of women’s mental health
research. Psychiatr Clin North Am 2003; 26(3):781-99.
2. American College of Obstetricians and Gynecologists Committee on
Ethics. At-risk drinking and illicit drug use: Ethical issues in obstetric
and gynecological practice. Committee on Opinion no. 294: ACOG: Washington
DC, 2004 pp 1-11.
3. Agarwal P, Rajadurai VS, Bhavani S, Tan KW. Perinatal drug abuse
in KK Women’s and Children’s Hospital. Ann Acad Med Singapore 1999;
28(6):765-9.
4. Armstrong MA, Lieberman L, Carpenter DM, Gonzales VM, Usatin MS,
Newman L, Escobar GJ. Early start: An obstetric clinic-based, perinatal
substance abuse intervention program. Qual Manag Health Care 2001; 9(2):6-
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5. Goler NC, Armstrong MA, Taillac CJ, Osejo VM. Substance abuse
treatment linked with prenatal visits improves perinatal outcomes: a new
standard. J Perinatol 2008; 28(9):597-603.
6. Barclay L. Medicaid Codes will allow billing for alcohol, drug
screening and brief intervention. Medscape Medical News 2006. Available
at: http://www.medscape.com/viewarticle/544548_print
Conflict of Interest:
None declared