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Thomas H. Inge, Go Miyano, Judy Bean, Michael Helmrath, Anita Courcoulas, Carroll M. Harmon, Mike K. Chen, Kimberly Wilson, Stephen R. Daniels, Victor F. Garcia, Mary L. Brandt, and Lawrence M. Dolan
Reversal of Type 2 Diabetes Mellitus and Improvements in Cardiovascular Risk Factors After Surgical Weight Loss in Adolescents
Pediatrics 2009; 123: 214-222 [Abstract] [Full text] [PDF]
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[Read eLetters] Gastric Bypass for obesity in children: Too much – Too Late!
Diana L. Farmer, MD   (4 February 2009)

Gastric Bypass for obesity in children: Too much – Too Late! 4 February 2009
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Diana L. Farmer, MD,
Pediatric Surgeon
University of California, San Francisco

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Re: Gastric Bypass for obesity in children: Too much – Too Late!

diana.farmer{at}ucsfmedctr.org Diana L. Farmer, MD

First, my congratulations to Dr. Inge and his colleagues for continuing to bring responsibility and rationality to this charged area of surgery in children. While I am pleased that he has shown that Gastric Bypass Surgery can reduce the severity of type 2 diabetes, I suggest that it is the weight loss that reverses diabetes and not the surgery. Unfortunately, this is not a randomized trial nor does it compare results to a cohort of obese patients with similar non-surgical weight loss. One has to ask the question – success at what price?

We all now know that weight loss can be achieved without surgery just from watching “The Biggest Loser” on TV. It is a tragic indictment of our society that we can spend $10-40K cutting the stomachs and rearranging the intestines of our children, but we cannot spend 1/10 of that amount in diet and exercise programs to prevent and reverse this problem. Dr. Inge knows that I respectfully object to Gastric Bypass Surgery in children for many reasons:

1. While co-morbidities are serious, children are not dying from obesity before the age of 18, and the surgery still carries a finite peri- operative mortality rate. How many dead children are justified?

2. We do not know the long-term implications of having one’s stomach cut away from the flow of intestinal contents yet “parked” in the abdomen for potentially 60-80 years with no ability to access via endoscopy. Will there be an increase in gastric cancers, ulcers, etc.?

3. We do know that the bypass operation involves some degree of nutrient malabsorption, risking pernicious anernia, calcium malabsorption and bone density problems, as well as folate malabsorption with a potential increase in birth defects in subsequent pregnancy. We also do know that teens are notoriously non-compliant with parental recommendations to take vitamins (and most other friendly parental advice to teenagers).

4. Children and teenagers cannot consent to this permanently GI- and life-altering operation. Their parents do this for (to) them. In fact, our clinical psychology colleagues inform us that the cognitive ability to understand mortality does not occur until approximately age 25. (Hence, the enthusiasm of our young soldiers and the ease of abuse of childhood combatant recruits in some countries.)

Further, it is hard not to believe that given feverish pace of drug company research into obesity, and the rapid advances in understanding the neuro-endocrine-GI contributors to appetite control coupled with known drugs and conditions with serious appetite suppression, that a medical aid to weight loss will be developed in the next 5-10 years. Then what do we do with all these re-routed stomachs? (Not to mention the children’s stomachs that went into the pathology bucket! Hey Mom, I want my stomach back!) Obesity surgery is a problem of too much, too late. We must seriously attack childhood obesity in the young (6-7 year olds) when we stand the best chance to change behavior. We should enroll them in serious diet and exercise programs and, if necessary, take them out of school for 6 months or a year (as a child with cancer or other serious illnesses) and spend time and money to treat this problem.

Indeed if all fails, they can have bypass surgery as an adult when they have achieved growth, had their children, and most importantly, can understand the life-long risks of mortality, cancer, adhesive bowel obstructions, internal hernias, flatulence, and give their own informed consent. While I applaud the Cincinnati Children’s Group and colleagues for venturing into this difficult area in the most responsible way possible, I chastise those that do this as a part-time effort without rigorous life- long follow-up and study and my adult obesity colleagues who treat children as adults without regard to their unique cognitive status and those who pursue this highly remunerative surgery for monetary gain.

I have had several pediatricians call me saying they have a patient who just had surgery for obesity – they have no idea what kind of surgery (except perhaps a path report “normal stomach”), and they have no idea how to manage their eating, what to do when the patient gets gastroenteritis or abdominal pain and are looking for guidance.

Finally, pediatricians are the gatekeepers and guardians of our youth. You should not allow non-pediatric surgeons to operate on children except in extraordinary circumstances and then only after you have interrogated their training and experience with children. You must think long and hard before you recommend a “quick surgical fix” for a chronic behavioral problem.

Sadly, long-term studies in adults suggest that even with gastric bypass surgery, weight loss may not be durable and weight often returns after 10 years. For a patient with 50+ years to go, that is significant!

Conflict of Interest:

None declared