Peter S. Millard, MD, PhD, Physician Family Medicine Residency Program
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Re: Consistent effects of pacifier use to prevent SIDS?
pmillard{at}emh.org Peter S. Millard, MD, PhD
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Mitchell, Blair and L'Hoir present a systematic review of 8
epidemiologic studies concerning pacifier use and SIDS. However, the
methods of their systematic review do not adhere to the standards
recommended by the Cochrane Collaboration (1). In particular, they do not
demonstrate that they conducted a comprehensive search for all studies on
pacifier use and SIDS, nor do they report on their inclusion/exclusion
criteria or tell us which studies they excluded. They do not report on the
validity of included studies, and their only statement on heterogeneity is
that "The results are remarkably consistent." In fact, the results do not
appear to me to be consistent, with adjusted odd ratios ranging from 0.24
to 1.47. Did the authors use a fixed or random effects model? Did they
conduct a statistical test of heterogeneity before concluding that the
results were consistent between studies?
1. Cochrane Handbook for Systematic Reviews of Interventions.
http://www.cochrane.org/resources/handbook/
Conflict of Interest:
None declared |