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REVIEW ARTICLES:
Scott A. Shipman, Mark Helfand, Virginia A. Moyer, and Barbara P. Yawn
Screening for Developmental Dysplasia of the Hip: A Systematic Literature Review for the US Preventive Services Task Force
Pediatrics 2006; 117: e557-e576 [Abstract] [Full text] [PDF]
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[Read eLetters] A Systematic review with a blind eye?
Ruediger von Kries   (29 May 2006)

A Systematic review with a blind eye? 29 May 2006
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Ruediger von Kries,
Pediatrician
Munich University

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Re: A Systematic review with a blind eye?

Prof.von.Kries{at}GMX.de Ruediger von Kries

Shipman and colleagues can be congratulated for their comprehensive review of the literature on screening for Developmental Dysplasia of the Hip (DDH). There are indeed many issues about screening for DDH we should know more about. At least one paper, however, seems to have escaped their attention.

Active surveillance data covering about 750 000 births annually over a five year period have shown that operative procedures for DDH are quite low in a population with an ongoing ultrasound screening program: 0.26/100 000 live births (1). These figures are much lower than previously established rates for operative procedures for DDH in the same population prior to the introduction of the ultrasound screening program: 1/100 000 (2). Additionally these rates are much lower than in other populations with clinical screening only: 0.46, 0.78 and 1.03 / 100 000 live births in Australia, UK and Ireland respectively (3-5).

This low rate could neither be explained by under ascertainment since it was based on active surveillance with capture recapture correction for underreporting nor by a too narrow case definition: As in other publications the case definition was wide including closed reductions, open reductions and osteotomy (1).

The ultrasound screening program in Germany, however, did not prevent all operative procedures for DDH. There were still 0.26 operative procedures per 100 000 live births (1) despite a widely accepted and implemented ultrasound screening program. About half these cases were in children with early ultrasound diagnosis and therapy within the first 10 weeks suggesting that operative procedures might not be completely prevented by early diagnosis and treatment of DDH. The remaining cases regarded were related to delayed screening, potentially spuriously normal ultrasound findings or unscreened children.

These prospective data from a population with about 750 000 births per year does provide evidence for a substantial reduction in the rate of operative procedures for DDH by an ultrasound screening program. The rate of operative procedures for DDH was an accepted benchmark for the assessment of ultrasound screening programs in the systematic review.

Why was this paper ignored while others with an identical methodological approach were included in the review (3-5)?

References:

1. von-Kries R, Ihme N, Oberle D, Lorani A, Stark R, Altenhofen L, et al. Effect of ultrasound screening on the rate of first operative procedures for developmental hip dysplasia in Germany. Lancet 2003;362(9399):1883-7.

2. Katthagen B.-D. MH, Becker D. Häufigkeit und stationärer Behandlungsbeginn kindlicher Hüftgelenksluxationen in der BR Deuschland. Z. Orthop. 1988;126:475 - 483.

3. Chan A, Cundy PJ, Foster BK, Keane RJ, Byron-Scott R. Late diagnosis of congenital dislocation of the hip and presence of a screening programme: South Australian population-based study. Lancet 1999;354(9189):1514-7.

4. Godward S, Dezateux C. Surgery for congenital dislocation of the hip in the UK as a measure of outcome of screening. Lancet 1998;351:1149- 1152.

5. Maxwell SL, Ruiz AL, Lappin KJ, Cosgrove AP. Clinical screening for developmental dysplasia of the hip in Northern Ireland. Bmj 2002;324(7344):1031-3.

Conflict of Interest:

None declared