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ARTICLES:
Minesh Khashu, Horacio Osiovich, Deborah Henry, Aziz Al Khotani, Alfonso Solimano, and David P. Speert
Persistent Bacteremia and Severe Thrombocytopenia Caused by Coagulase-Negative Staphylococcus in a Neonatal Intensive Care Unit
Pediatrics 2006; 117: 340-348 [Abstract] [Full text] [PDF]
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[Read P3R] Coagulase negative Staph and Thrombocytopenia
Mushtaq Ahmad Bhat, Wajid Ali,Mudasir sultana   (3 March 2006)

Coagulase negative Staph and Thrombocytopenia 3 March 2006
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Mushtaq Ahmad Bhat,
Associate professor
SKIMS Soura,
Wajid Ali,Mudasir sultana

Send letter to journal:
Re: Coagulase negative Staph and Thrombocytopenia

mbhat47{at}rediffmail.com Mushtaq Ahmad Bhat, et al.

The article written by Minesh Khusoo and others is remarkable in that for the first time increased morbidity has been shown to be caused by coagulase negativen staph in neonates from a developed country.We have seen a similar pattern of thrombocytopenia and increased morbidity and mortality caused not only by coagulase negative Staph but also by gram negative organisms causing persistent bacteremia in neonates.In our study at Sherikashmir Institute of medical sciences India,26 neonates developed septicemia because of coagulase negative staph over a period of two years and persistent bacteremia and thrombocytopenia was seen in 17 patients(65%).Many of these organisms were methicillin resistant and were treated with vancomycin.The increased incidence was in preterm vetilated babies. Out of these 26 patients 3/26(11%) died and rest of the babies were discharged.There was increased incidence of GI bleed,,delayed initiation of feeds,feeding intolerance in these patients.Coagulase negative staph causing thrombocytopenia and increased morbidity in our set up is very common in neonates

Conflict of Interest:

None declared