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TABLE 1. Levels of Adrenal Androgens in Normal-Weight and Obese Children

Normal Weight Mean (Range) Overweight Mean (Range) Obese Mean (Range) P^a

Girls

    Testosterone, ng/mL 0.11 (0.06–0.20) 0.14 (0.10–0.21) 0.16 (0.09–0.24) .112

    DHEAS, µg/mL 0.71 (0.41–1.10) 0.85 (0.61–1.15) 0.88 (0.57–1.21)^b .081

     ${Delta}$ ⁴-A, ng/mL 0.4 (0.2–0.8)^b 0.6 (0.4–1.1)^b 0.6 (0.4–0.8)^b <.05^b

    IGF-1, ng/mL 199 (140–318) 236 (180–283) 200 (190–266) .681

Boys

    Testosterone, ng/mL 0.08 (0.04–0.15)^b 0.17 (0.06–0.26)^b 0.28 (0.09–0.39)^b <.05^b

    DHEAS, µg/mL 0.51 (0.21–0.92) 1.10 (0.82–1.24)^b 1.12 (0.20–2.12) .056

     ${Delta}$ ⁴-A, ng/mL 0.4 (0.2–0.7) 0.5 (0.3–0.6) 0.6 (0.4–1.0) .524

    IGF-1, ng/mL 200 (89–257)^b 170 (116–207)^b 288 (267–369)^b <.05^b

^a Kruskal-Wallis test.

^b Results were significant.

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