Published online September 1, 2006
PEDIATRICS Vol. 118 No. 3 September 2006, pp. 1313-1314 (doi:10.1542/peds.2006-1197)
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LETTER TO THE EDITOR

The Apgar Score

Mary Anne Whelan, PhD, MD
Community Health and Behavioral Services
Cerebral Palsy of Upstate New York
Utica, NY 13501

To the Editor.—

The recent policy statement concerning the Apgar score1 is internally contradictory and factually incorrect and should not have been presented as a policy statement of the sponsoring institutions. Clearly driven by an effort to oppose the use of low Apgar scores as litigious weapons, it suffers from persistent confusion between Apgar scores as indicators of asphyxia and Apgar scores as predictors of outcomes.

Concerning internal contradictions, we note the statement that "[t]he Apgar score has been used inappropriately in term infants to predict specific neurologic outcome." However, it is also acknowledged that "A retrospective analysis concluded that the 5-minute Apgar score remained a valid predictor of neonatal mortality" and "another study indicated that low Apgar scores at 5 minutes are associated with death or cerebral palsy, and this association increased if both 1- and 5-minute scores were low." Death and motor impairment are certainly specific neurologic outcomes.

The principal conveyed message, namely, that Apgar scores do not correlate with neurologic outcomes, is incorrect and directly contradicted by published evidence, including that presented in articles that are cited in the statement. No correlative study has failed to find an association between Apgar score and neurologic outcome. Several available studies do conclude that Apgar scores correlate with neurologic outcomes, in both term and premature infants, and argue that Apgar scores may be used as guidelines to the desirability of resuscitation.27 The authors argue that the Apgar score is reflective of condition, not etiology of condition, and that its predictive value is not absolute within certain time frames and ranges. This may be true, but it does not obviate the fact that correlation of low Apgar scores with negative outcome is indeed present at all time periods. The Collaborative Perinatal Project8 found the risk of cerebral palsy in surviving infants with a 1-minute score of ≤3 to be 8 times the risk of those with scores of >6. Thirty-four percent of the infants with scores of ≤3 at 10 minutes died. Furthermore, we may be sure that the more subtle neurologic deficits of learning and behavioral difficulties have been consistently underestimated in studies that followed patients for limited time periods and with relatively simplistic criteria. This issue has not been addressed.

Although it is understandable that we wish to support our obstetrical colleagues in refuting the misuse of Apgar scores as tools of indictment of damaging (and remunerative) mismanagement, the issues of what they represent and what they predict need to be separated. The educational and operational implications of this article are not acceptable. To quote from a recent review cited by the authors, "We conclude that the Apgar system continues to be relevant to the prediction of neonatal outcome after almost half a century."9

FOOTNOTES

Statements appearing here are those of the writers and do not represent the offcial position of the American Academy of Pediatrics or its Committees. Comments on any topic, including the contents of PEDIATRICS, are invited from all members of the profession; those accepted for publication will not be subject to major editorial revision but generally must be no more than 400 words in length. The editors reserve the right to publish replies and may solicit responses from authors and others.

Please see www.pediatrics.org for instructions on submitting letters.

REFERENCES

  1. American Academy of Pediatrics, Committee on Fetus and Newborn; American College of Obstetricians and Gynecologists, Committee on Obstetric Practice. The Apgar Score. Pediatrics. 2006; 117: 1444–1447[Abstract/Free Full Text]
  2. Patel H, Beeby PJ. Resuscitation beyond 10 minutes of term babies born without signs of life. J Paediatr Child Health. 2004;40 :136 –138[CrossRef][ISI][Medline]
  3. Tanir HM, Sener T, Tekin N, Aksit A, Ardic N. Preterm premature rupture of membranes and neonatal outcomes prior to 34 weeks of gestation. Int J Gynaecol Obstet. 2003;82 :167 –172[CrossRef][Medline]
  4. Ondoa-Onama C, Tumwine JK. Immediate outcome of babies with low Apgar score in Mulago Hospital, Uganda. East Afr Med J. 2003;80 :22 –29[Medline]
  5. Moster D, Lie RT, Irgens LM, Bjerkedal T, Markestad T. The association of Apgar score with subsequent death and cerebral palsy: a population-based study in term infants. J Pediatr. 2001;138 :798 –803[CrossRef][ISI][Medline]
  6. Asakura H, Ichikawa H, Nakabayashi M, et al. Perinatal risk factors related to neurologic outcomes of term newborns with asphyxia at birth: a prospective study. J Obstet Gynaecol Res. 2000;26 :313 –324[Medline]
  7. Haddad B, Mercer BM, Livingston JC, Talati A, Sibai BM. Outcome after successful resuscitation of babies born with Apgar scores of 0 at both 1 and 5 minutes. Am J Obstet Gynecol. 2000;182 :1210 –1214[CrossRef][ISI][Medline]
  8. Nelson KB, Ellenberg JH. Apgar scores as predictors of chronic neurologic disability. Pediatrics. 1981;68 :36 –84[Abstract/Free Full Text]
  9. Papile LA. The Apgar score in the 21st century. N Engl J Med. 2001:344 :519 –520[Free Full Text]

PEDIATRICS (ISSN 1098-4275). ©2006 by the American Academy of Pediatrics




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