Published online December 1, 2004
PEDIATRICS Vol. 114 No. 6 December 2004, pp. 1746 (doi:10.1542/peds.2004-2138)
ERRATUM
An error appeared in the article by Franz et al, titled "Measurement of Interleukin 8 in Combination With C-Reactive Protein Reduced Unnecessary Antibiotic Therapy in Newborn Infants: A Multicenter, Randomized, Controlled Trial," that was published in the July 2004 issue of Pediatrics (2004;114:18). On page 3 it reads: "On the basis of these assumptions, a sample size of 207 patients with infection in each group was required to demonstrate one-sided equivalence of the proportion of initially mixed infections. Assuming a rate of bacterial infections of 18% in the study population, a total of 1150 patients had to be enrolled into the study." The numbers of patients are incorrect: they were copied from an outdated protocol version that assumed an equivalence limit of 1%. However, when drafting the final protocol the authors decided to accept an equivalence limit of 0.03 (as reported in the manuscript). Assuming the equivalence limit of 0.03 (i.e., 3%) this section should read as follows: "On the basis of these assumptions, a sample size of 117 patients with infection in each group was required to demonstrate one-sided equivalence of the proportion of initially mixed infections. Assuming a rate of bacterial infections of 18% in the study population, a total of 650 patients in each group had to be enrolled into the study."
PEDIATRICS (ISSN 1098-4275). ©2004 by the American Academy of Pediatrics
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