| Year |
Patient
|
| 1997 |
1994 |
2000 |
2002 |
2001 |
1999 |
2002 |
2001 |
|
| Admitting hospital |
Hadassah Mt. Scopus Jerusalem, Israel |
Hospital for Sick Children, Toronto, Canada |
Hadassah Ein Karem, Jerusalem, Israel |
Soroka University Medical Center, Beer Sheva, Israel |
Sheba Medical Center, Tel Aviv, Israel |
| Birth weight (gestational age) |
1880 g (35 wk) |
3980 g (41 wk) |
3170 g (40 wk) |
3475 g (40 wk) |
3200 g (40 wk) |
4100 g (42 wk) |
3155 g (40 wk) |
2800 g (40 wk) |
| Age (d) at circumcision |
31 |
8 |
16 |
8 |
8 |
8 |
8 |
8 |
| Days from circumcision at presentation |
4 |
9 |
4 |
9 |
6 |
11 |
8 |
7 |
| Temperature |
38.0°C |
38.1°C |
38.2°C |
38.5°C |
36.1°C |
37.0°C |
38.0°C |
38.4°C |
| Serology of mother (infant) |
Negative (negative) |
Negative (negative) |
Negative (negative) |
Negative (negative) |
Negative (negative) |
Negative (negative) |
Positive 1:16 (positive 1:16) |
Negative (negative) |
| Serology mohel |
N/A |
Positive (>1:64) |
N/A |
N/A |
N/A |
Positive |
Positive (1:64)* |
Positive (1.64)* |
| Initial treatment (acyclovir in mg/kg/day) |
IV acyclovir x 8 d |
IV acyclovir x 26 d x 10 d |
IV acyclovir x 10 d + PO acyclovir x 14 d |
IV acyclovir x 8 d + PO acyclovir x 2 d |
No treatment |
No treatment |
IV acyclovir x 21 d |
IV acyclovir x 14 d |
| Course and treatment |
4 recurrences over 8 mo; treated with PO acyclovir x 4 d |
Discharged after 26 d IV acyclovir, no neurologic deficit; treated with local acyclovir ointment |
5 episodes over 20 mo, treated with local acyclovir ointment |
3 episodes over 7 mo, treated with local acyclovir ointment |
Spontaneous recovery |
Spontaneous recovery |
4 d in intensive care unit as a result of seizures (same dosage of acyclovir) |
5 more episodes over 11 mo with positive HSV cultures from lesions; treated with PO-acyclovir x 7–14 d |
| Long-term outcome |
Prophylactic treatment with acyclovir for 1 y, normal development |
N/A |
Delayed psychomotor development |
N/A |
>2 mo N/A |
> 3 mo N/A |
Infantile spasm, hipsarrythmia |
Prophylactic treatment with acyclovir, normal development |
