Published online July 13, 2009
PEDIATRICS Vol. 124 No. 2 August 2009, pp. 799-801 (doi:10.1542/peds.2009-1045)
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COMMENTARY

Early Pubertal Development in Chinese Girls

Barbara Cromer, MDa,b and Catherine M. Gordon, MD, MScc

a Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio
b Division of Adolescent Medicine, Department of Pediatrics, MetroHealth Medical Center, Cleveland, Ohio
c Bone Health Program, Divisions of Adolescent Medicine and Endocrinology, Children's Hospital Boston, Boston, Massachusetts

Abbreviations: ED—endocrine disruptor • SPAN—Study of Puberty Across the Nation

The first 20% of the full text of this article appears below.

In this issue of Pediatrics, Huamei et al1 report on a cross-sectional study of 20654 healthy Chinese girls aged 3 to 19.83 years to identify stages of breast and pubic hair development. The median age for breast Tanner stage 2 was 9.20 years (95% confidence interval: 9.06–9.32) and for pubic hair Tanner stage 2 was 11.16 years (95% confidence interval: 11.03–11.29). The concern we are putting forth here is the possibility of a secular trend in early puberty2 and its potential link to toxins in the environment.

Increasing recognition of a possible secular trend in early breast development among girls in this country, and possible environmental determinants, resulted in the convening of a multidisciplinary expert panel sponsored jointly by the US Environmental Protection Agency, the National Institute of Environmental Sciences, and Serono Symposia International. The findings from this workshop were published in Pediatrics in 2008.3–6 The majority of the panelists agreed that there was sufficient evidence to suggest a trend in younger age for onset of . . . [Full Text of this Article]

Address correspondence to Barbara Cromer, MD, MetroHealth Medical Center, Division of Adolescent Medicine, 2500 MetroHealth Dr, Cleveland, OH 44109. E-mail: bcromer@metrohealth.org


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