Published online October 31, 2008
PEDIATRICS Vol. 122 No. 5 November 2008, pp. 1153-1154 (doi:10.1542/peds.2008-2152)
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LETTER TO THE EDITOR

Importance of On-time RotaTeq Vaccination and Long-term Active Surveillance

Evan J. Anderson, MD
Divisions of Infectious Diseases,
Departments of Pediatrics and Medicine,
Children's Memorial and Northwestern Memorial Hospitals,
Northwestern University Feinberg School of Medicine,
Chicago, IL 60614

The first 20% of the full text of this article appears below.

To the Editor.—

I read with great interest the article by Haber et al,1 who studied intussusception after implementation of RotaTeq vaccination by using the passive Vaccine Adverse Event Reporting System (VAERS) and the active Vaccine Safety Datalink (VSD) surveillance systems. Two important points bear mentioning.

First, data from this study should not be misconstrued to support RotaTeq administration outside the US Food and Drug Administration (FDA)–licensed window.2 Although debated, reanalysis of the RotaShield data suggests that much of the risk of intussusception occurred in patients receiving RotaShield late (eg, first dose at 4 or 6 months).3–5 Compliance . . . [Full Text of this Article]


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